PDB: 297 resultsInfo pagesStatus searchChemie searchBIRD

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6TXR	Structural insights into cubane-modified aptamer recognition of a malaria biomarker Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... Authors: Cheung, Y, Roethlisberger, P, Mechaly, A, Weber, P, Wong, A, Lo, Y, Haouz, A, Savage, P, Hollenstein, M, Tanner, J. Deposit date: 2020-01-14 Release date: 2020-07-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker. Proc.Natl.Acad.Sci.USA, 117, 2020
7NAY	Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH. Descriptor: 1,2-ETHANEDIOL, BORIC ACID, L-lactate dehydrogenase, ... Authors: Bertrand, Q, Robin, A, Girard, E, Madern, D. Deposit date: 2021-01-25 Release date: 2021-02-10 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases. J.Struct.Biol., 215, 2023
1CET	CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE. Descriptor: N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, PROTEIN (L-LACTATE DEHYDROGENASE) Authors: Read, J.A, Wilkinson, K.W, Tranter, R, Sessions, R.B, Brady, R.L. Deposit date: 1999-03-10 Release date: 1999-03-19 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase. J.Biol.Chem., 274, 1999
4ROS	Crystal structure of Methylobacterium extorquens malate dehydrogenase complexed with oxaloacetate and adenosine-5-diphosphoribose Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Malate dehydrogenase, ... Authors: Gonzalez, J.M, Marti-Arbona, R, Unkefer, C.J. Deposit date: 2014-10-28 Release date: 2014-12-17 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of Methylobacterium extorquens malate dehydrogenase complexed with oxaloacetate and adenosine-5-diphosphoribose To be Published
1CIV	CHLOROPLAST NADP-DEPENDENT MALATE DEHYDROGENASE FROM FLAVERIA BIDENTIS Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-MALATE DEHYDROGENASE Authors: Carr, P.D, Ashton, A.R, Verger, D, Ollis, D.L. Deposit date: 1999-04-01 Release date: 2000-04-05 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Chloroplast NADP-malate dehydrogenase: structural basis of light-dependent regulation of activity by thiol oxidation and reduction. Structure Fold.Des., 7, 1999
1D3A	CRYSTAL STRUCTURE OF THE WILD TYPE HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM Descriptor: CHLORIDE ION, HALOPHILIC MALATE DEHYDROGENASE, SODIUM ION Authors: Richard, S.B, Madern, D, Garcin, E, Zaccai, G. Deposit date: 1999-09-28 Release date: 2000-03-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.94 Å) Cite: Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 A resolution structures of the wild type and a mutant of malate dehydrogenase from Haloarcula marismortui. Biochemistry, 39, 2000
1CEQ	CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE. Descriptor: PROTEIN (L-LACTATE DEHYDROGENASE) Authors: Read, J.A, Wilkinson, K.W, Tranter, R, Sessions, R.B, Brady, R.L. Deposit date: 1999-03-10 Release date: 1999-03-19 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2 Å) Cite: Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase. J.Biol.Chem., 274, 1999
4RLS	Lactate Dehydrogenase in complex with inhibitor compound 47 Descriptor: (1R)-5'-[(2-chlorophenyl)sulfanyl]-4'-hydroxy-2,3-dihydrospiro[indene-1,2'-pyran]-6'(3'H)-one, (2S)-2-HYDROXYPROPANOIC ACID, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... Authors: Eigenbrot, C, Ultsch, M.H. Deposit date: 2014-10-17 Release date: 2014-11-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 24, 2014
4TVO	Structure of Malate Dehydrogenase from Mycobacterium tuberculosis Descriptor: Malate dehydrogenase, SODIUM ION, SULFATE ION Authors: Ferraris, D.M, Rizzi, M. Deposit date: 2014-06-27 Release date: 2015-01-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis. Proteins, 83, 2015
5ES3	Co-crystal structure of LDH liganded with oxamate Descriptor: L-lactate dehydrogenase A chain, OXAMIC ACID Authors: Nowicki, M.W, Wear, M.A, McNae, I.W, Blackburn, E.A. Deposit date: 2015-11-16 Release date: 2016-01-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.29 Å) Cite: A Streamlined, Automated Protocol for the Production of Milligram Quantities of Untagged Recombinant Rat Lactate Dehydrogenase A Using AKTAxpressTM. Plos One, 10, 2015
4UUL	Apo trichomonas vaginalis lactate dehydrogenase L91R Descriptor: L-LACTATE DEHYDROGENASE Authors: Steindel, P.A, Chen, E.H, L Theobald, D. Deposit date: 2014-07-29 Release date: 2015-08-12 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
6H9S	Crystal dimeric structure of Petrotoga mobilis lactate dehydrogenase with NADH Descriptor: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Roche, J, Engilberge, S, Girard, E, Madern, D. Deposit date: 2018-08-06 Release date: 2018-08-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of Petrotoga mobilis lactate dehydrogenase at 1.9 Angstrom resolution To Be Published
6ITL	Crystal structure of malate dehydrogenase from Mannheimia succiniciproducens in complex with NAD Descriptor: GLYCEROL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Seo, H, Kim, K.-J. Deposit date: 2018-11-23 Release date: 2019-11-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase. Nat Commun, 11, 2020
6IHE	Crystal structure of Malate dehydrogenase from Metallosphaera sedula Descriptor: 1,2-ETHANEDIOL, D-MALATE, DI(HYDROXYETHYL)ETHER, ... Authors: Lee, D, Kim, K.J. Deposit date: 2018-09-29 Release date: 2019-02-06 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
6IHD	Crystal structure of Malate dehydrogenase from Metallosphaera sedula Descriptor: 2-ETHOXYETHANOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Lee, D, Kim, K.J. Deposit date: 2018-09-29 Release date: 2019-02-06 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
5HTO	Crystal structure of Plasmodium Vivax LDH in complex with a DNA aptamer called pL1 (tetrameric LDH in an asymmetric unit) Descriptor: DNA (30-MER), DNA (34-MER), L-lactate dehydrogenase, ... Authors: Choi, S.J, Ban, C. Deposit date: 2016-01-27 Release date: 2016-10-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
5HS4	Plasmdoium Vivax Lactate dehydrogenase Descriptor: L-lactate dehydrogenase Authors: Choi, S.J, Ban, C. Deposit date: 2016-01-25 Release date: 2016-10-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.339 Å) Cite: Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
5HRU	Crystal structure of Plasmodium vivax LDH in complex with a DNA aptamer called pL1 Descriptor: DNA (32-MER), L-lactate dehydrogenase, MAGNESIUM ION Authors: Choi, S.J, Ban, C. Deposit date: 2016-01-24 Release date: 2016-10-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Crystal structure of a DNA aptamer bound to PvLDH elucidates novel single-stranded DNA structural elements for folding and recognition Sci Rep, 6, 2016
5NQB	Rabbit Muscle L-lactate dehydrogenase in complex with malonate Descriptor: L-lactate dehydrogenase A chain, MALONATE ION Authors: Luisi, B.F, Olin-Sandoval, V. Deposit date: 2017-04-19 Release date: 2017-05-03 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.58 Å) Cite: The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. Nat Commun, 8, 2017
5NFR	Crystal structure of malate dehydrogenase from Plasmodium falciparum (PfMDH) Descriptor: CITRIC ACID, Malate dehydrogenase Authors: Lunev, S, Romero, A.R, Batista, F.A, Wrenger, C, Groves, M.R. Deposit date: 2017-03-15 Release date: 2018-01-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro. PLoS ONE, 13, 2018
5NQQ	Rabbit Muscle L-lactate dehydrogenase in complex with NADH and oxaloacetate Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, OXALOACETATE ION, ... Authors: Luisi, B.F, Olin-Sandoval, V. Deposit date: 2017-04-20 Release date: 2017-06-07 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.872 Å) Cite: The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization. Nat Commun, 8, 2017
5NUF	Cytosolic Malate Dehydrogenase 1 Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Young, D, Messens, J, Huang, J, Reichheld, J.-P. Deposit date: 2017-04-29 Release date: 2018-01-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
5NUE	Cytosolic Malate Dehydrogenase 1 (peroxide-treated) Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-ETHOXYETHANOL, ... Authors: Young, D, Messens, J, Huang, J, Reichheld, J.-P. Deposit date: 2017-04-29 Release date: 2018-02-28 Last modified: 2018-07-04 Method: X-RAY DIFFRACTION (1.35000277 Å) Cite: Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. J. Exp. Bot., 69, 2018
2PWZ	Crystal structure of the apo form of E.Coli malate dehydrogenase Descriptor: Malate dehydrogenase Authors: Soderberg, C.A.G, Clarke, T.A, Richardson, D.J, Hemmings, A.M. Deposit date: 2007-05-14 Release date: 2007-05-29 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The X-ray crystal structure of the apo form of E.Coli malate dehydrogenase in space group C2 To be Published
2V6B	Crystal structure of lactate dehydrogenase from Deinococcus Radiodurans (apo form) Descriptor: L-LACTATE DEHYDROGENASE Authors: Coquelle, N, Fioravanti, E, Weik, M, Vellieux, F. Deposit date: 2007-07-16 Release date: 2007-09-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments. J. Mol. Biol., 374, 2007

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