1CEQ
CHLOROQUINE BINDS IN THE COFACTOR BINDING SITE OF PLASMODIUM FALCIPARUM LACTATE DEHYDROGENASE.
Summary for 1CEQ
Entry DOI | 10.2210/pdb1ceq/pdb |
Descriptor | PROTEIN (L-LACTATE DEHYDROGENASE) (2 entities in total) |
Functional Keywords | oxidoreductase, tricarboxylic acid cycle, inhibitor |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Total number of polymer chains | 1 |
Total formula weight | 34164.71 |
Authors | Read, J.A.,Wilkinson, K.W.,Tranter, R.,Sessions, R.B.,Brady, R.L. (deposition date: 1999-03-10, release date: 1999-03-19, Last modification date: 2023-08-09) |
Primary citation | Read, J.A.,Wilkinson, K.W.,Tranter, R.,Sessions, R.B.,Brady, R.L. Chloroquine binds in the cofactor binding site of Plasmodium falciparum lactate dehydrogenase. J.Biol.Chem., 274:10213-10218, 1999 Cited by PubMed: 10187806DOI: 10.1074/jbc.274.15.10213 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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