PDB: 41454 resultsInfo pagesStatus searchChemie searchBIRD

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8G7W	Type I modPKS reducing region Descriptor: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... Authors: McCullough, T.M, Smith, J.L. Deposit date: 2023-02-17 Release date: 2023-06-07 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structure of a modular polyketide synthase reducing region. Structure, 31, 2023
8GJX	Structure of the human STING receptor bound to 2'3'-cUA Descriptor: 2'3'-cUA, Stimulator of interferon genes protein Authors: Morehouse, B.R, Li, Y, Slavik, K.M, Toyoda, H, Kranzusch, P.J. Deposit date: 2023-03-16 Release date: 2023-07-05 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.6 Å) Cite: cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
4EMT	Crystal Structure of human STING bound to c-di-GMP Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173 Authors: Li, P. Deposit date: 2012-04-12 Release date: 2012-06-13 Last modified: 2012-07-25 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19, 2012
4IRL	X-ray structure of the CARD domain of zebrafish GBP-NLRP1 like protein Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Jin, T, Huang, M, Smith, P, Xiao, T. Deposit date: 2013-01-15 Release date: 2013-08-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Structure of the caspase-recruitment domain from a zebrafish guanylate-binding protein. Acta Crystallogr.,Sect.F, 69, 2013
4EMU	Crystal structure of ligand free human STING Descriptor: CALCIUM ION, Transmembrane protein 173 Authors: Li, P. Deposit date: 2012-04-12 Release date: 2012-06-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat.Struct.Mol.Biol., 19, 2012
3R0L	Crystal structure of crotoxin Descriptor: ACETATE ION, CHLORIDE ION, Crotoxin chain A, ... Authors: Saul, F.A, Faure, G. Deposit date: 2011-03-08 Release date: 2011-10-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Crystal Structure of Crotoxin Reveals Key Residues Involved in the Stability and Toxicity of This Potent Heterodimeric Beta-Neurotoxin J.Mol.Biol., 412, 2011
7Y8T	Structure of Cas7-11-crRNA in complex with TPR-CHAT Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (37-MER), ... Authors: Wang, S, Guo, M, Zhu, Y, Huang, Z. Deposit date: 2022-06-24 Release date: 2023-06-28 Last modified: 2024-01-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT. Cell Res., 32, 2022
7Y8Y	Structure of Cas7-11-crRNA-tgRNA in complex with TPR-CHAT Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (37-MER), ... Authors: Wang, S, Guo, M, Zhu, Y, Huang, Z. Deposit date: 2022-06-24 Release date: 2023-06-28 Last modified: 2024-01-10 Method: ELECTRON MICROSCOPY (3 Å) Cite: Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT. Cell Res., 32, 2022
4JLH	HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor Descriptor: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, HIV-1 Integrase catalytic core domain, SULFATE ION Authors: Feng, L, Kvaratskhelia, M. Deposit date: 2013-03-12 Release date: 2013-05-01 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.09 Å) Cite: The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors. J.Biol.Chem., 288, 2013
5D4N	Structure of CPII bound to ADP, AMP and acetate, from Thiomonas intermedia K12 Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Wheatley, N.M, Ngo, J, Cascio, D, Sawaya, M.R, Yeates, T.O. Deposit date: 2015-08-08 Release date: 2016-09-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein. J.Mol.Biol., 428, 2016
6DLW	Complement component polyC9 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement component C9, beta-D-mannopyranose Authors: Dunstone, M.A, Spicer, B.A, Law, R.H.P. Deposit date: 2018-06-03 Release date: 2018-09-12 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: The first transmembrane region of complement component-9 acts as a brake on its self-assembly. Nat Commun, 9, 2018
7XSJ	The structure of the Mint1/Munc18-1/syntaxin-1 complex Descriptor: Amyloid-beta A4 precursor protein-binding family A member 1, Syntaxin-1A, Syntaxin-binding protein 1 Authors: Feng, W, Li, W. Deposit date: 2022-05-14 Release date: 2022-11-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.2 Å) Cite: A non-canonical target-binding site in Munc18-1 domain 3b for assembling the Mint1-Munc18-1-syntaxin-1 complex. Structure, 31, 2023
7XSP	Structure of gRAMP-target RNA Descriptor: RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*G)-3'), ... Authors: Feng, Y, Zhang, L.X. Deposit date: 2022-05-15 Release date: 2022-11-09 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
7XSS	Structure of Craspase-CTR Descriptor: CHAT domain protein, RAMP superfamily protein, RNA (34-MER), ... Authors: Feng, Y, Zang, L.X. Deposit date: 2022-05-15 Release date: 2022-11-09 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
7Y85	CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to self RNA target Descriptor: CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... Authors: Zhang, J.T, Cui, N, Huang, H.D, Jia, N. Deposit date: 2022-06-22 Release date: 2022-12-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.73 Å) Cite: Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
7Y81	CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to non-self RNA target Descriptor: MAGNESIUM ION, Non-self RNA target, RAMP superfamily protein, ... Authors: Zhang, J.T, Cui, N, Huang, H.D, Jia, N. Deposit date: 2022-06-22 Release date: 2022-12-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
7Y80	CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA binary complex Descriptor: MAGNESIUM ION, RAMP superfamily protein, ZINC ION, ... Authors: Zhang, J.T, Cui, N, Huang, H.D, Jia, N. Deposit date: 2022-06-22 Release date: 2022-12-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
7Y82	CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to self RNA target Descriptor: MAGNESIUM ION, RAMP superfamily protein, Self RNA target, ... Authors: Zhang, J.T, Cui, N, Huang, H.D, Jia, N. Deposit date: 2022-06-22 Release date: 2022-12-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.83 Å) Cite: Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
7Y83	CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to non-self RNA target Descriptor: CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... Authors: Zhang, J.T, Cui, N, Huang, H.D, Jia, N. Deposit date: 2022-06-22 Release date: 2022-12-14 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase. Nat Commun, 13, 2022
6KML	2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli Descriptor: Antitoxin HigA, mRNA interferase toxin HigB Authors: Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. Deposit date: 2019-07-31 Release date: 2020-11-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.095 Å) Cite: 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin. Biochem.J., 477, 2020
6KMQ	2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli Descriptor: Antitoxin HigA, mRNA interferase toxin HigB Authors: Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. Deposit date: 2019-07-31 Release date: 2020-11-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.35 Å) Cite: 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin. Biochem.J., 477, 2020
6KWA	AtDAO1(dioxygenase for auxin oxidation 1 from Arabidopsis thaliana) Descriptor: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein, MAGNESIUM ION Authors: Rhee, S, Jin, S, Lee, H. Deposit date: 2019-09-06 Release date: 2020-11-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.09429145 Å) Cite: Crystal structure of the indole-3-acetic acid-catabolizing enzyme DAO1 from Arabidopsis thaliana. J.Struct.Biol., 212, 2020
7XSO	Structure of the type III-E CRISPR-Cas effector gRAMP Descriptor: RAMP superfamily protein, RNA (35-MER), ZINC ION Authors: Feng, Y, Zhang, L. Deposit date: 2022-05-15 Release date: 2023-03-22 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Target RNA activates the protease activity of Craspase to confer antiviral defense. Mol.Cell, 82, 2022
6DGV	iGABASnFR Fluorescent GABA Sensor precursor Descriptor: Fluorescent GABA Sensor precursor Authors: Marvin, J.S, Looger, L.L. Deposit date: 2018-05-18 Release date: 2019-04-03 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A genetically encoded fluorescent sensor for in vivo imaging of GABA. Nat.Methods, 16, 2019
3F5T	X-ray Structure of H5N1 NS1 Descriptor: Nonstructural protein 1 Authors: Bornholdt, Z.A, Prasad, B.V.V. Deposit date: 2008-11-04 Release date: 2008-11-25 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus Nature, 456, 2008

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