3NZ1
| Crystal Structure of Kemp Elimination Catalyst 1A53-2 Complexed with Transition State Analog 5-Nitro Benzotriazole | Descriptor: | 5-nitro-1H-benzotriazole, Indole-3-glycerol phosphate synthase, L(+)-TARTARIC ACID, ... | Authors: | Lee, T.M, Privett, H.K, Kaiser, J.T, Mayo, S.L. | Deposit date: | 2010-07-15 | Release date: | 2011-06-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Iterative approach to computational enzyme design. Proc.Natl.Acad.Sci.USA, 109, 2012
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4ERN
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4EYE
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3OPF
| Crystal structure of TTHA0988 in space group P212121 | Descriptor: | GLYCEROL, Putative uncharacterized protein TTHA0988, SULFATE ION | Authors: | Jacques, D.A, Kuramitsu, S, Yokoyama, S, Trewhella, J, Guss, J.M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2010-09-01 | Release date: | 2011-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase Acta Crystallogr.,Sect.D, 67, 2011
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3OQ9
| Structure of the FAS/FADD death domain assembly | Descriptor: | Protein FADD, Tumor necrosis factor receptor superfamily member 6 | Authors: | Kabaleeswaran, V, Wu, H. | Deposit date: | 2010-09-02 | Release date: | 2010-10-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (6.8 Å) | Cite: | The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations. Nat.Struct.Mol.Biol., 17, 2010
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3OQI
| Crystal structure of B. licheniformis CDPS yvmC-BLIC in complex with CHES | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Putative uncharacterized protein yvmC | Authors: | Bonnefond, L, Arai, T, Suzuki, T, Ishitani, R, Nureki, O. | Deposit date: | 2010-09-03 | Release date: | 2011-02-23 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog. Proc.Natl.Acad.Sci.USA, 108, 2011
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3P3E
| Crystal Structure of the PSEUDOMONAS AERUGINOSA LpxC/LPC-009 complex | Descriptor: | N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, NITRATE ION, SODIUM ION, ... | Authors: | Lee, C.-J, Zhou, P. | Deposit date: | 2010-10-04 | Release date: | 2011-01-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chem.Biol., 18, 2011
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3OVJ
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3P3G
| Crystal Structure of the Escherichia coli LpxC/LPC-009 complex | Descriptor: | 4-ethynyl-N-[(1S,2R)-2-hydroxy-1-(oxocarbamoyl)propyl]benzamide, DIMETHYL SULFOXIDE, N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, ... | Authors: | Lee, C.-J, Zhou, P. | Deposit date: | 2010-10-04 | Release date: | 2011-01-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chem.Biol., 18, 2011
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3OMU
| Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative | Descriptor: | 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide, Heat shock protein 83 | Authors: | Wernimont, A.K, Hutchinson, A, Sullivan, H, Weadge, J, Cossar, D, Li, Y, Kozieradzki, I, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Wyatt, P.G, Fairlamb, A.H, MacKenzie, C, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | Deposit date: | 2010-08-27 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design. PLoS Negl Trop Dis, 7, 2013
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3OZ6
| Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960 | Descriptor: | GLYCEROL, Mitogen-activated protein kinase 1, serine/threonine protein kinase | Authors: | Wernimont, A.K, Lew, J, Lin, Y.H, Sullivan, H, Hassanali, A, Kozieradzki, I, Cossar, D, Arrowsmith, C.H, Bochkarev, A, Bountra, C, Edwards, A.M, Weigelt, J, Hui, R, Neculai, A.M, Hutchinson, A, Structural Genomics Consortium (SGC) | Deposit date: | 2010-09-24 | Release date: | 2010-12-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960 To be Published
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3OVL
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3NFW
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3OWF
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V66R at cryogenic temperature | Descriptor: | CALCIUM ION, PHOSPHATE ION, THYMIDINE-3',5'-DIPHOSPHATE, ... | Authors: | Schlessman, J.L, Khangulov, V, Heroux, A, Garcia-Moreno E, B. | Deposit date: | 2010-09-17 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Domain swapping promoted by a single mutation that introduces an ionizable group into the hydrophobic core of a protein To be Published
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3P1E
| Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO) | Descriptor: | CREB-binding protein, DIMETHYL SULFOXIDE, POTASSIUM ION, ... | Authors: | Filippakopoulos, P, Picaud, S, Feletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-09-30 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO) To be Published
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3P5M
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7K5I
| SARS-COV-2 nsp1 in complex with human 40S ribosome | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Wang, L, Shi, M, Wu, H. | Deposit date: | 2020-09-16 | Release date: | 2020-10-14 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv, 2020
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4EVO
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3P4I
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4EWW
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-04-28 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EX0
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-04-29 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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3PDR
| Crystal structure of manganese bound M-box RNA | Descriptor: | M-box Riboswitch RNA, MANGANESE (II) ION, POTASSIUM ION | Authors: | Ramesh, A, Winkler, W.C. | Deposit date: | 2010-10-23 | Release date: | 2011-02-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.853 Å) | Cite: | Insights into Metalloregulation by M-box Riboswitch RNAs via Structural Analysis of Manganese-Bound Complexes. J.Mol.Biol., 407, 2011
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4EXT
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4EYN
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-01 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.532 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4F0O
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-04 | Release date: | 2013-05-08 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (1.672 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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