Human Insulin

Summary for 4EYN

Related4EWW 4EWX 4EWZ 4EX0 4EX1 4EXX 4EY1 4EY9 4EYD 4EYP
DescriptorInsulin A chain, Insulin B chain, ZINC ION, ... (5 entities in total)
Functional Keywordshormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11837.03
Favero-Retto, M.P.,Palmieri, L.C.,Lima, L.M.T.R. (deposition date: 2012-05-01, release date: 2013-05-01, Last modification date: 2017-11-15)
Primary citation
Favero-Retto, M.P.,Palmieri, L.C.,Souza, T.A.,Almeida, F.C.,Lima, L.M.
Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85:1112-1121, 2013
PubMed: 23692694 (PDB entries with the same primary citation)
DOI: 10.1016/j.ejpb.2013.05.005
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.281140 1.1% 9.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25