3P1E

Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO)

Summary for 3P1E

• Entry DOI: 10.2210/pdb3p1e/pdb
• Related: 3P1C 3P1D 3P1F
• Descriptor: CREB-binding protein, THIOCYANATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: structural genomics consortium, sgc, cbp, crebbp, creb binding protein isoform a, kat3a, rsts, rst, bromodomain, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q92793
• Total number of polymer chains: 2
• Total formula weight: 28700.14

Authors

Filippakopoulos, P.,Picaud, S.,Feletar, I.,Fedorov, O.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-09-30, release date: 2010-11-24, Last modification date: 2023-09-06)

• Primary citation: Filippakopoulos, P.,Picaud, S.,Feletar, I.,Fedorov, O.,Muniz, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of the bromodomain of human CREBBP in complex with dimethyl sulfoxide (DMSO); To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)