2XM3
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![BU of 2xm3 by Molmil](/molmil-images/mine/2xm3) | Deinococcus radiodurans ISDra2 Transposase Left end DNA complex | Descriptor: | 5'-D(*TP*TP*AP*GP*T)-3', ACETATE ION, DRA2 TRANSPOSASE BINDING ELEMENT, ... | Authors: | Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. | Deposit date: | 2010-07-22 | Release date: | 2010-10-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
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5ULX
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8U6X
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![BU of 8u6x by Molmil](/molmil-images/mine/8u6x) | ATP-dependent DNA ligase Lig E from Neisseria gonorrhoeae | Descriptor: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*CP*CP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*T)-3'), ... | Authors: | Williamson, A, Pan, J. | Deposit date: | 2023-09-14 | Release date: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | A role for the ATP-dependent DNA ligase lig E of Neisseria gonorrhoeae in biofilm formation. Bmc Microbiol., 24, 2024
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5ULW
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![BU of 5ulw by Molmil](/molmil-images/mine/5ulw) | |
7EF9
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![BU of 7ef9 by Molmil](/molmil-images/mine/7ef9) | Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form II) | Descriptor: | Adenine DNA glycosylase, DNA (5'-D(*AP*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), ... | Authors: | Nakamura, T, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2021-03-21 | Release date: | 2021-06-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
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7EF8
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![BU of 7ef8 by Molmil](/molmil-images/mine/7ef8) | Crystal structure of mouse MUTYH in complex with DNA containing AP site analogue:8-oxoG (Form I) | Descriptor: | Adenine DNA glycosylase, DNA (5'-D(*TP*AP*GP*TP*CP*CP*CP*(3DR)P*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*CP*T)-3'), ... | Authors: | Nakamura, T, Nakabeppu, Y, Yamagata, Y. | Deposit date: | 2021-03-21 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. Nucleic Acids Res., 49, 2021
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8U3Y
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![BU of 8u3y by Molmil](/molmil-images/mine/8u3y) | SpG Cas9 with NGG PAM DNA target | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | Authors: | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | Deposit date: | 2023-09-08 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8TZZ
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![BU of 8tzz by Molmil](/molmil-images/mine/8tzz) | SpG Cas9 with NGC PAM DNA target | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | Authors: | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | Deposit date: | 2023-08-28 | Release date: | 2024-05-01 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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6AJR
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![BU of 6ajr by Molmil](/molmil-images/mine/6ajr) | Complex form of Uracil DNA glycosylase X and uracil | Descriptor: | IRON/SULFUR CLUSTER, URACIL, Uracil DNA glycosylase superfamily protein | Authors: | Ahn, W.C, Aroli, S, Varshney, U, Woo, E.J. | Deposit date: | 2018-08-28 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.341 Å) | Cite: | Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision. Nat.Chem.Biol., 15, 2019
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6AJP
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![BU of 6ajp by Molmil](/molmil-images/mine/6ajp) | Complex form of Uracil DNA glycosylase X and deoxyuridine monophosphate. | Descriptor: | 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein | Authors: | Ahn, W.C, Aroli, S, Varshney, U, Woo, E.J. | Deposit date: | 2018-08-28 | Release date: | 2019-05-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.334 Å) | Cite: | Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision. Nat.Chem.Biol., 15, 2019
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6AJQ
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![BU of 6ajq by Molmil](/molmil-images/mine/6ajq) | E52Q mutant form of Uracil DNA glycosylase X from Mycobacterium smegmatis. | Descriptor: | IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein | Authors: | Ahn, W.C, Aroli, S, Varshney, U, Woo, E.J. | Deposit date: | 2018-08-28 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.342 Å) | Cite: | Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision. Nat.Chem.Biol., 15, 2019
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2HAJ
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6AJS
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![BU of 6ajs by Molmil](/molmil-images/mine/6ajs) | H109S mutant form of Uracil DNA glycosylase X. | Descriptor: | IRON/SULFUR CLUSTER, Uracil DNA glycosylase superfamily protein | Authors: | Ahn, W.C, Aroli, S, Varshney, U, Woo, E.J. | Deposit date: | 2018-08-28 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.632 Å) | Cite: | Covalent binding of uracil DNA glycosylase UdgX to abasic DNA upon uracil excision. Nat.Chem.Biol., 15, 2019
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3NGD
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3K0S
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![BU of 3k0s by Molmil](/molmil-images/mine/3k0s) | Crystal structure of E.coli DNA mismatch repair protein MutS, D693N mutant, in complex with GT mismatched DNA | Descriptor: | 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP*GP*AP*C*AP*CP*T*GP*GP*TP*GP*CP*TP*TP*GP*GP*CP*AP*GP*CP*T)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Reumer, G.A, Winterwerp, H.H.K, Sixma, T.K. | Deposit date: | 2009-09-25 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS. J.Biol.Chem., 285, 2010
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2OYQ
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![BU of 2oyq by Molmil](/molmil-images/mine/2oyq) | Crystal structure of RB69 gp43 in complex with DNA with 5-NIMP opposite an abasic site analog | Descriptor: | 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ... | Authors: | Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. | Deposit date: | 2007-02-22 | Release date: | 2007-10-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
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4PU3
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![BU of 4pu3 by Molmil](/molmil-images/mine/4pu3) | Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121) | Descriptor: | Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | Deposit date: | 2014-03-12 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
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4DKJ
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![BU of 4dkj by Molmil](/molmil-images/mine/4dkj) | CpG specific methyltransferase in complex with target DNA | Descriptor: | Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... | Authors: | Wojciechowski, M, Czapinska, H, Bochtler, M. | Deposit date: | 2012-02-03 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI. Proc.Natl.Acad.Sci.USA, 110, 2013
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8A71
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![BU of 8a71 by Molmil](/molmil-images/mine/8a71) | Crystal structure of right-handed Z-DNA containing 2'-deoxy-L-ribose in complex with the polyamine cadaverine and potassium cations at ultrahigh resolution | Descriptor: | 5-azaniumylpentylazanium, POTASSIUM ION, Right-handed Z-DNA | Authors: | Drozdzal, P, Manszewski, T, Gilski, M, Brzezinski, K, Jaskolski, M. | Deposit date: | 2022-06-20 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (0.69 Å) | Cite: | Right-handed Z-DNA at ultrahigh resolution: a tale of two hands and the power of the crystallographic method. Acta Crystallogr D Struct Biol, 79, 2023
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5D9I
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![BU of 5d9i by Molmil](/molmil-images/mine/5d9i) | SV40 Large T antigen origin binding domain bound to artificial DNA fork | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Meinke, G, Bohm, A, Bullock, P.A. | Deposit date: | 2015-08-18 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA. J. Virol., 85, 2011
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8B6E
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![BU of 8b6e by Molmil](/molmil-images/mine/8b6e) | crystal structure of the DNA-binding short chromatophore-targeted protein sCTP-23166 from Paulinella chromatophora | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, sCTP-23166 | Authors: | Macorano, L, Applegate, V, Hoeppner, A, Smits, S.H.J, Nowack, E.C.M. | Deposit date: | 2022-09-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore. Proc.Natl.Acad.Sci.USA, 120, 2023
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3U7G
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![BU of 3u7g by Molmil](/molmil-images/mine/3u7g) | Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTAp) | Descriptor: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | Authors: | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | Deposit date: | 2011-10-13 | Release date: | 2011-12-14 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
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6U8X
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![BU of 6u8x by Molmil](/molmil-images/mine/6u8x) | Crystal structure of DNMT3B-DNMT3L in complex with CpApG DNA | Descriptor: | CpApG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Gao, L, Song, J. | Deposit date: | 2019-09-06 | Release date: | 2020-06-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95063877 Å) | Cite: | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
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6GN3
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![BU of 6gn3 by Molmil](/molmil-images/mine/6gn3) | Racemic crystal structure of A-DNA duplex formed from d(CCCGGG) in space group P21/n | Descriptor: | CHLORIDE ION, COBALT (II) ION, DNA (5'-D(*CP*CP*CP*GP*GP*G)-3'), ... | Authors: | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | Deposit date: | 2018-05-29 | Release date: | 2019-09-11 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Racemic crystal structures of A-DNA duplexes. Acta Crystallogr D Struct Biol, 78, 2022
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3U7H
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![BU of 3u7h by Molmil](/molmil-images/mine/3u7h) | Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp) | Descriptor: | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... | Authors: | Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. | Deposit date: | 2011-10-13 | Release date: | 2011-12-14 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
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