3K0S

Crystal structure of E.coli DNA mismatch repair protein MutS, D693N mutant, in complex with GT mismatched DNA

Summary for 3K0S

• Entry DOI: 10.2210/pdb3k0s/pdb
• Related: 1E3M 1W7A
• Descriptor: DNA mismatch repair protein mutS, 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*CP*AP*CP*CP*AP*GP*TP*GP*TP*CP*AP*GP*CP*GP*TP*CP*CP*TP*AP*T)-3', 5'-D(*AP*TP*AP*GP*GP*AP*CP*GP*CP*TP*GP*AP*C*AP*CP*T*GP*GP*TP*GP*CP*TP*TP*GP*GP*CP*AP*GP*CP*T)-3', ... (5 entities in total)
• Functional Keywords: magnesium mutant, dna repair protein, protein-dna complex, atp-binding, dna damage, dna repair, dna-binding, nucleotide-binding, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Escherichia coli; More
• Total number of polymer chains: 4
• Total formula weight: 197836.41

Authors

Reumer, G.A.,Winterwerp, H.H.K.,Sixma, T.K. (deposition date: 2009-09-25, release date: 2010-02-16, Last modification date: 2023-09-06)

• Primary citation: Lebbink, J.H.,Fish, A.,Reumer, A.,Natrajan, G.,Winterwerp, H.H.,Sixma, T.K.; Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.; J.Biol.Chem., 285:13131-13141, 2010; PubMed: 20167596; DOI: 10.1074/jbc.M109.066001

Experimental method

X-RAY DIFFRACTION (2.2 Å)