3K0S

Crystal structure of E.coli DNA mismatch repair protein MutS, D693N mutant, in complex with GT mismatched DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000018	biological_process	regulation of DNA recombination
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006281	biological_process	DNA repair
A	0006298	biological_process	mismatch repair
A	0006974	biological_process	DNA damage response
A	0008301	molecular_function	DNA binding, bending
A	0016887	molecular_function	ATP hydrolysis activity
A	0030983	molecular_function	mismatched DNA binding
A	0032136	molecular_function	adenine/cytosine mispair binding
A	0032300	cellular_component	mismatch repair complex
A	0042802	molecular_function	identical protein binding
A	0043531	molecular_function	ADP binding
A	0140664	molecular_function	ATP-dependent DNA damage sensor activity
A	1990710	cellular_component	MutS complex
B	0000018	biological_process	regulation of DNA recombination
B	0000166	molecular_function	nucleotide binding
B	0003677	molecular_function	DNA binding
B	0003684	molecular_function	damaged DNA binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006281	biological_process	DNA repair
B	0006298	biological_process	mismatch repair
B	0006974	biological_process	DNA damage response
B	0008301	molecular_function	DNA binding, bending
B	0016887	molecular_function	ATP hydrolysis activity
B	0030983	molecular_function	mismatched DNA binding
B	0032136	molecular_function	adenine/cytosine mispair binding
B	0032300	cellular_component	mismatch repair complex
B	0042802	molecular_function	identical protein binding
B	0043531	molecular_function	ADP binding
B	0140664	molecular_function	ATP-dependent DNA damage sensor activity
B	1990710	cellular_component	MutS complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE ADP A 1801

Chain	Residue
A	PHE596
A	THR622
A	HIS760
A	HOH905
A	HOH996
A	HOH1055
A	ILE597
A	ASN599
A	ASN616
A	MET617
A	GLY618
A	GLY619
A	LYS620
A	SER621

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY614
B	GLY614

---