5F0S
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![BU of 5f0s by Molmil](/molmil-images/mine/5f0s) | Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion | Descriptor: | DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... | Authors: | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | Deposit date: | 2015-11-28 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
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2UUA
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![BU of 2uua by Molmil](/molmil-images/mine/2uua) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin. | Descriptor: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines. Nat. Struct. Mol. Biol., 14, 2007
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6SO9
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![BU of 6so9 by Molmil](/molmil-images/mine/6so9) | |
7OGJ
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![BU of 7ogj by Molmil](/molmil-images/mine/7ogj) | |
5NKK
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![BU of 5nkk by Molmil](/molmil-images/mine/5nkk) | SMG8-SMG9 complex GDP bound | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Li, L, Basquin, J, Conti, E. | Deposit date: | 2017-03-31 | Release date: | 2017-04-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins. RNA, 23, 2017
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5BJR
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![BU of 5bjr by Molmil](/molmil-images/mine/5bjr) | |
5F0Q
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![BU of 5f0q by Molmil](/molmil-images/mine/5f0q) | Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer | Descriptor: | DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... | Authors: | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | Deposit date: | 2015-11-28 | Release date: | 2016-03-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
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7OHU
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![BU of 7ohu by Molmil](/molmil-images/mine/7ohu) | |
7OHY
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![BU of 7ohy by Molmil](/molmil-images/mine/7ohy) | |
1MWL
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![BU of 1mwl by Molmil](/molmil-images/mine/1mwl) | |
3J7O
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![BU of 3j7o by Molmil](/molmil-images/mine/3j7o) | Structure of the mammalian 60S ribosomal subunit | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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2KI7
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![BU of 2ki7 by Molmil](/molmil-images/mine/2ki7) | The solution structure of RPP29-RPP21 complex from Pyrococcus furiosus | Descriptor: | Ribonuclease P protein component 1, Ribonuclease P protein component 4, ZINC ION | Authors: | Xu, Y, Foster, M.P. | Deposit date: | 2009-04-28 | Release date: | 2009-09-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of an archaeal RNase P binary protein complex: formation of the 30-kDa complex between Pyrococcus furiosus RPP21 and RPP29 is accompanied by coupled protein folding and highlights critical features for protein-protein and protein-RNA interactions. J.Mol.Biol., 393, 2009
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4H4L
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![BU of 4h4l by Molmil](/molmil-images/mine/4h4l) | Crystal Structure of ternary complex of HutP(HutP-L-His-Zn) | Descriptor: | HISTIDINE, Hut operon positive regulatory protein, ZINC ION | Authors: | Dhakshnamoorthy, B, Misono, T.S, Mizuno, H, Kumar, P.K.R. | Deposit date: | 2012-09-17 | Release date: | 2013-09-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Alternative binding modes of l-histidine guided by metal ions for the activation of the antiterminator protein HutP of Bacillus subtilis. J.Struct.Biol., 183, 2013
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5A0V
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![BU of 5a0v by Molmil](/molmil-images/mine/5a0v) | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | Descriptor: | 5'-R(*CP*GP*CP*CP*UP*CP)-3', CYTIDINE-5'-MONOPHOSPHATE, RIBONUCLEASE J, ... | Authors: | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | Deposit date: | 2015-04-23 | Release date: | 2015-08-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J Nucleic Acids Res., 43, 2015
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5A0T
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![BU of 5a0t by Molmil](/molmil-images/mine/5a0t) | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | Descriptor: | 5'-R(*CP*GP*CP*CP*UP)-3', DI(HYDROXYETHYL)ETHER, RIBONUCLEASE J, ... | Authors: | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | Deposit date: | 2015-04-22 | Release date: | 2015-08-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.283 Å) | Cite: | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J Nucleic Acids Res., 43, 2015
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4ZLD
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![BU of 4zld by Molmil](/molmil-images/mine/4zld) | Crystal structure of human Roquin-2 ROQ domain in complex with Roquin CDE RNA | Descriptor: | GLYCEROL, RNA (5'-R(*UP*AP*AP*CP*UP*UP*CP*UP*GP*UP*GP*AP*AP*GP*UP*UP*G)-3'), Roquin-2 | Authors: | Sakurai, S, Ohto, U, Shimizu, T. | Deposit date: | 2015-05-01 | Release date: | 2015-08-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of human Roquin-2 and its complex with constitutive-decay element RNA Acta Crystallogr.,Sect.F, 71, 2015
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5UDK
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![BU of 5udk by Molmil](/molmil-images/mine/5udk) | IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | Deposit date: | 2016-12-27 | Release date: | 2017-03-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDJ
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![BU of 5udj by Molmil](/molmil-images/mine/5udj) | IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), ... | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | Deposit date: | 2016-12-27 | Release date: | 2017-03-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDI
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![BU of 5udi by Molmil](/molmil-images/mine/5udi) | IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap) | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | Deposit date: | 2016-12-27 | Release date: | 2017-03-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDL
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![BU of 5udl by Molmil](/molmil-images/mine/5udl) | IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap) | Descriptor: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | Authors: | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | Deposit date: | 2016-12-27 | Release date: | 2017-03-01 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3J7Q
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![BU of 3j7q by Molmil](/molmil-images/mine/3j7q) | Structure of the idle mammalian ribosome-Sec61 complex | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2019-10-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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5X89
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![BU of 5x89 by Molmil](/molmil-images/mine/5x89) | The X-ray crystal structure of subunit fusion RNA splicing endonuclease from Methanopyrus kandleri | Descriptor: | EndA-like protein,tRNA-splicing endonuclease, PHOSPHATE ION | Authors: | Kaneta, A, Fujishima, K, Morikazu, W, Hori, H, Hirata, A. | Deposit date: | 2017-03-01 | Release date: | 2018-01-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | The RNA-splicing endonuclease from the euryarchaeaon Methanopyrus kandleri is a heterotetramer with constrained substrate specificity Nucleic Acids Res., 46, 2018
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6UU7
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![BU of 6uu7 by Molmil](/molmil-images/mine/6uu7) | E. coli sigma-S transcription initiation complex with a 6-nt RNA and an NTP ("Old" crystal soaked with UTP, CTP, ddGTP, and dinucleotide ApG for 30 minutes) | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, De, S, Steitz, T.A. | Deposit date: | 2019-10-30 | Release date: | 2020-08-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6ZU5
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![BU of 6zu5 by Molmil](/molmil-images/mine/6zu5) | Structure of the Paranosema locustae ribosome in complex with Lso2 | Descriptor: | 18S rRNA, 25S rRNA, 5S rRNA, ... | Authors: | Ehrenbolger, K, Jespersen, N, Sharma, H, Sokolova, Y.Y, Tokarev, Y.S, Vossbrinck, C.R, Barandun, J. | Deposit date: | 2020-07-21 | Release date: | 2020-11-04 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Differences in structure and hibernation mechanism highlight diversification of the microsporidian ribosome. Plos Biol., 18, 2020
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6TYF
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![BU of 6tyf by Molmil](/molmil-images/mine/6tyf) | Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer | Descriptor: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Molodtsov, V, Ebright, R.H. | Deposit date: | 2019-08-08 | Release date: | 2020-03-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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