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5WWX
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BU of 5wwx by Molmil
Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA
Descriptor: NICKEL (II) ION, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C
Authors:Yang, L, Wang, C, Li, F, Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWT
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BU of 5wwt by Molmil
Crystal structure of human NSun6/tRNA
Descriptor: Putative methyltransferase NSUN6, tRNA
Authors:Liu, R.J, Long, T, Wang, E.D.
Deposit date:2017-01-04
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
5WWS
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BU of 5wws by Molmil
Crystal structure of human NSun6/tRNA/SAM
Descriptor: Putative methyltransferase NSUN6, S-ADENOSYLMETHIONINE, tRNA
Authors:Liu, R.J, Long, T, Wang, E.D.
Deposit date:2017-01-04
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.247 Å)
Cite:Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
4R0E
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BU of 4r0e by Molmil
Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R
Descriptor: RNA-directed RNA polymerase
Authors:Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
Deposit date:2014-07-30
Release date:2014-11-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase.
J.Biol.Chem., 289, 2014
5NS4
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BU of 5ns4 by Molmil
Crystal structures of Cy3 cyanine fluorophores stacked onto the end of double-stranded RNA
Descriptor: 3-[(2~{Z})-2-[(~{E})-3-[3,3-dimethyl-1-(3-oxidanylpropyl)indol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethyl-indol-1-yl]propan-1-ol, 50S ribosomal protein L5, MAGNESIUM ION, ...
Authors:Liu, Y.J, Lilley, D.M.J.
Deposit date:2017-04-25
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA.
Biophys. J., 113, 2017
6PZQ
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BU of 6pzq by Molmil
Structure of the human respiratory syncytial virus M2-1 protein in complex with a short positive-sense gene-end RNA
Descriptor: Matrix M2-1, RNA (5'-R(P*GP*UP*UP*AP*AP*U)-3'), ZINC ION
Authors:Gao, Y, Cao, D, Liang, B.
Deposit date:2019-08-01
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Structure of the Human Respiratory Syncytial Virus M2-1 Protein in Complex with a Short Positive-Sense Gene-End RNA.
Structure, 28, 2020
6O5F
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BU of 6o5f by Molmil
Crystal structure of DEAD-box RNA helicase DDX3X at pre-unwound state
Descriptor: ATP-dependent RNA helicase DDX3X, CHLORIDE ION, RNA (5'-R(P*CP*AP*AP*GP*GP*UP*CP*AP*UP*UP*CP*GP*CP*AP*AP*GP*AP*GP*UP*GP*GP*CP*C)-3')
Authors:Song, H, Ji, X.
Deposit date:2019-03-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X.
Nat Commun, 10, 2019
5WQ1
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BU of 5wq1 by Molmil
Solution Structure of the first stem-loop of Escherichia coli DsrA RNA
Descriptor: DsrA-SL1
Authors:Wu, P, Wu, J, Shi, Y.
Deposit date:2016-11-22
Release date:2017-07-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The important conformational plasticity of DsrA sRNA for adapting multiple target regulation
Nucleic Acids Res., 45, 2017
6SDY
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BU of 6sdy by Molmil
Solution structure of Staufen1 dsRBD4 - hARF1 SBS dsRNA complex.
Descriptor: Double-stranded RNA-binding protein Staufen homolog 1, hARF1 SBS dsRNA
Authors:Yadav, D.K, Lukavsky, P.J.
Deposit date:2019-07-29
Release date:2020-01-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition.
Nucleic Acids Res., 48, 2020
8HIM
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BU of 8him by Molmil
A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom
Descriptor: DNA (34-MER), DNA-directed RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, ...
Authors:Hu, H, Xie, G, Du, X, Du, J.
Deposit date:2022-11-21
Release date:2023-03-22
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure and mechanism of the plant RNA polymerase V.
Science, 379, 2023
5YTX
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BU of 5ytx by Molmil
Crystal structure of YB1 cold-shock domain in complex with UCAACU
Descriptor: Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*UP*CP*AP*AP*CP*U)-3')
Authors:Yang, X, Huang, Y.
Deposit date:2017-11-20
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.551 Å)
Cite:Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.
J.Biol.Chem., 294, 2019
5YTT
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BU of 5ytt by Molmil
Crystal structure of YB1 cold-shock domain in complex with UCAUGU
Descriptor: Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*UP*CP*AP*UP*GP*U)-3'), SULFATE ION
Authors:Yang, X, Huang, Y.
Deposit date:2017-11-20
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.
J.Biol.Chem., 294, 2019
5YTV
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BU of 5ytv by Molmil
Crystal structure of YB1 cold-shock domain in complex with UCAUCU
Descriptor: Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*UP*CP*AP*UP*CP*U)-3')
Authors:Yang, X, Huang, Y.
Deposit date:2017-11-20
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.
J.Biol.Chem., 294, 2019
5YTS
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BU of 5yts by Molmil
Crystal structure of YB1 cold-shock domain in complex with UCUUCU
Descriptor: Nuclease-sensitive element-binding protein 1, RNA (5'-R(P*CP*UP*UP*C)-3'), SULFATE ION
Authors:Yang, X, Huang, Y.
Deposit date:2017-11-20
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of a Y-box binding protein 1 (YB-1)-RNA complex reveals key features and residues interacting with RNA.
J.Biol.Chem., 294, 2019
6N67
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BU of 6n67 by Molmil
Crystal structure of the ligase domain of fungal tRNA ligase Trl1
Descriptor: CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GLYCEROL, ...
Authors:Peschek, J, Walter, P.
Deposit date:2018-11-26
Release date:2019-07-03
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:tRNA ligase structure reveals kinetic competition between non-conventional mRNA splicing and mRNA decay.
Elife, 8, 2019
6SDW
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BU of 6sdw by Molmil
Solution structure of Staufen1 dsRBD3+4 - hARF1 SBS dsRNA complex.
Descriptor: Double-stranded RNA-binding protein Staufen homolog 1, hARF1 SBS dsRNA
Authors:Yadav, D.K, Lukavsky, P.J.
Deposit date:2019-07-29
Release date:2020-01-15
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition.
Nucleic Acids Res., 48, 2020
5KI6
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BU of 5ki6 by Molmil
Human Argonaute-2 bound to a guide RNA with a nucleobase modification at position 1
Descriptor: PHENOL, Protein argonaute-2, miR-122
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2016-06-16
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:Structure-Guided Control of siRNA Off-Target Effects.
J.Am.Chem.Soc., 138, 2016
3L7Z
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BU of 3l7z by Molmil
Crystal structure of the S. solfataricus archaeal exosome
Descriptor: Probable exosome complex RNA-binding protein 1, Probable exosome complex exonuclease 1, Probable exosome complex exonuclease 2, ...
Authors:Lu, C, Ding, F, Ke, A.
Deposit date:2009-12-29
Release date:2010-06-23
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring.
Plos One, 5, 2010
4RZ9
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BU of 4rz9 by Molmil
Pre-mRNA-splicing factor 38A AS 1-179
Descriptor: Pre-mRNA-splicing factor 38A
Authors:Schuetze, T, Weber, G, Wahl, M.C.
Deposit date:2014-12-19
Release date:2015-12-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome
To be Published
8GZR
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BU of 8gzr by Molmil
Cryo-EM structure of the the NS5-NS3 RNA-elongation complex
Descriptor: CYTIDINE-5'-DIPHOSPHATE, Genome polyprotein, MANGANESE (II) ION, ...
Authors:Osawa, T, Ehara, H, Sekine, S.
Deposit date:2022-09-27
Release date:2023-08-02
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of dengue virus RNA replicase complexes.
Mol.Cell, 83, 2023
6HYU
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BU of 6hyu by Molmil
Crystal structure of DHX8 helicase bound to single stranded poly-adenine RNA
Descriptor: 1,2-ETHANEDIOL, ATP-dependent RNA helicase DHX8, RNA (5'-R(*A*AP*A)-3'), ...
Authors:Felisberto-Rodrigues, C, Thomas, J.C, McAndrew, P.C, Le Bihan, Y.V, Burke, R, Workman, P, van Montfort, R.L.M.
Deposit date:2018-10-22
Release date:2019-08-28
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release.
Biochem.J., 476, 2019
4RZA
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BU of 4rza by Molmil
Pre-mRNA-splicing factor 38A AS 1-205
Descriptor: Pre-mRNA-splicing factor 38A
Authors:Schuetze, T, Ulrich, A, Wahl, M.C.
Deposit date:2014-12-19
Release date:2015-12-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome
To be Published
5M8I
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BU of 5m8i by Molmil
Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA
Descriptor: CUGBP Elav-like family member 2, RNA (5'-R(*UP*UP*UP*AP*A)-3')
Authors:Diarra dit Konte, N, Damberger, F.F, Allain, F.H.T.
Deposit date:2016-10-28
Release date:2017-10-11
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Nat Commun, 8, 2017
4ROE
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BU of 4roe by Molmil
Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter
Descriptor: MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ...
Authors:Vannini, A, Gouge, J, Satia, K, Guthertz, N.
Deposit date:2014-10-28
Release date:2015-12-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
5EV1
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BU of 5ev1 by Molmil
Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2015-11-19
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.037 Å)
Cite:An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7, 2016

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