PDB: 222415 resultsInfo pagesStatus searchChemie searchBIRD

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4FGV	Crystal structure of free CRM1 (crystal form 1) Descriptor: Chromosome region maintenance 1 (CRM1) or Exportin 1 (Xpo1) Authors: Monecke, T, Neumann, P, Dickmanns, A, Ficner, R. Deposit date: 2012-06-05 Release date: 2013-01-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.941 Å) Cite: Structural basis for cooperativity of CRM1 export complex formation. Proc.Natl.Acad.Sci.USA, 110, 2013
4FJW	Crystal Structure of the apo form of the E131Q Mtb crotonase Descriptor: Probable enoyl-CoA hydratase echA8 Authors: Bruning, J.B, Delgado, E, Ghosh, S, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2012-06-12 Release date: 2013-05-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure and Mechanism of the Prokaryotic Crotonase To be Published
3CFT	Crystal structure of human transthyretin in complex with 1-amino-5-naphthalene sulfonate Descriptor: 5-aminonaphthalene-1-sulfonic acid, Transthyretin Authors: Lima, L.-M.T.R, Foguel, D, Polikarpov, I. Deposit date: 2008-03-04 Release date: 2009-03-03 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Identification of a novel ligand binding motif in the transthyretin channel. Bioorg.Med.Chem., 18, 2010
4FLI	Human MetAP1 with bengamide analog Y16, in Mn form Descriptor: (E,2R,3R,4S,5R)-N-(2-azanyl-2-oxidanylidene-ethyl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase 1, ... Authors: Ye, Q.Z, Xu, W. Deposit date: 2012-06-14 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem., 55, 2012
4FL5	Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS214 Descriptor: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... Authors: Schumacher, B, Ottmann, C. Deposit date: 2012-06-14 Release date: 2013-12-11 Last modified: 2017-06-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau. FASEB J., 29, 2015
3DTQ	Engineered human lipocalin 2 with specificity for Y-DTPA, apo-form Descriptor: Neutrophil gelatinase-associated lipocalin Authors: Eichinger, A, Skerra, A. Deposit date: 2008-07-15 Release date: 2009-05-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2. J.Am.Chem.Soc., 131, 2009
4FOV	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 3-Cyclohexyl-1-propylsulfonic acid Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPC	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Chlorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-chlorobenzyl)amino]ethanesulfonic acid, GLYCEROL, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FQ4	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(4-Fluoro-3-methylbenzyl)ammonio]ethanesulfonate Descriptor: 2-[(4-fluoro-3-methylbenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-25 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.843 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
3DUK	CRYSTAL STRUCTURE OF A NTF2-LIKE PROTEIN OF UNKNOWN FUNCTION (MFLA_0564) FROM METHYLOBACILLUS FLAGELLATUS KT AT 2.200 A RESOLUTION Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, NTF2-like protein of unknown function Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2008-07-17 Release date: 2008-12-23 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of NTF2-like protein of unknown function (YP_544675.1) from METHYLOBACILLUS FLAGELLATUS KT at 2.200 A resolution To be Published
4FMV	Crystal Structure Analysis of a GH30 Endoxylanase from Clostridium papyrosolvens C71 Descriptor: Glucuronoarabinoxylan endo-1,4-beta-xylanase Authors: Bales, E.B, Smith, J.K, St John, F.J, Hurlbert, J.C. Deposit date: 2012-06-18 Release date: 2013-06-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.01 Å) Cite: A novel member of glycoside hydrolase family 30 subfamily 8 with altered substrate specificity. Acta Crystallogr.,Sect.D, 70, 2014
4FOF	Crystal Structure of the blue-light absorbing form of the Thermosynechococcus elongatus PixJ GAF-domain Descriptor: Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form, ... Authors: Burgie, E.S, Walker, J.M, Phillips Jr, G.N, Vierstra, R.D. Deposit date: 2012-06-20 Release date: 2013-01-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.416 Å) Cite: A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes. Structure, 21, 2013
4FOY	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-(Benzylammonio)ethanesulfonate Descriptor: 2-(benzylamino)ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-21 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.843 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FPH	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Fluorobenzyl)ammonio]ethanesulfonate Descriptor: 2-[(3-fluorobenzyl)amino]ethanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B Authors: Brear, P. Deposit date: 2012-06-22 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.938 Å) Cite: Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases. Chembiochem, 13, 2012
4FQ9	Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa Descriptor: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, GLYCEROL, PHOSPHATE ION Authors: Moynie, L, Mcmahon, S.A, Duthie, F.G, Naismith, J.H. Deposit date: 2012-06-25 Release date: 2013-03-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa J.Mol.Biol., 425, 2013
4FRA	Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant Descriptor: DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, ... Authors: Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. Deposit date: 2012-06-26 Release date: 2013-12-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.43 Å) Cite: pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
4FI5	Crystal structure of the N-terminal domain of Hantaan virus strain 76-118 nucleoprotein Descriptor: Nucleoprotein Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-06-07 Release date: 2012-06-20 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the N-terminal domain of Hantaan virus strain 76-118 nucleoprotein TO BE PUBLISHED
3E1K	Crystal structure of Kluyveromyces lactis Gal80p in complex with the acidic activation domain of Gal4p Descriptor: Galactose/lactose metabolism regulatory protein GAL80, Lactose regulatory protein LAC9 Authors: Thoden, J.B, Holden, H.M. Deposit date: 2008-08-04 Release date: 2008-08-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: The Interaction between an Acidic Transcriptional Activator and Its Inhibitor: THE MOLECULAR BASIS OF Gal4p RECOGNITION BY Gal80p. J.Biol.Chem., 283, 2008
4FIC	Kinase domain of cSrc in complex with a hinge region-binding fragment Descriptor: 6-phenyl[1,2,4]triazolo[1,5-a]pyrazin-2-amine, Proto-oncogene tyrosine-protein kinase Src Authors: Richters, A, Rauh, D. Deposit date: 2012-06-08 Release date: 2013-04-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments. Acs Chem.Biol., 8, 2013
4FJO	Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex Descriptor: DNA polymerase kappa, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ... Authors: Wojtaszek, J, Lee, C.-J, Zhou, P. Deposit date: 2012-06-11 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.718 Å) Cite: Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric Pol zeta and Pol kappa J.Biol.Chem., 287, 2012
4FM9	Human topoisomerase II alpha bound to DNA Descriptor: DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ... Authors: Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M. Deposit date: 2012-06-15 Release date: 2012-08-08 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.901 Å) Cite: The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage. J.Mol.Biol., 424, 2012
4FLJ	Human MetAP1 with bengamide analog Y08, in Mn form Descriptor: (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase 1, ... Authors: Ye, Q.Z, Xu, W. Deposit date: 2012-06-14 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem., 55, 2012
4FND	Crystal structure of the Mtb enoyl CoA isomerase in complex with hydroxyhexanoyl CoA Descriptor: (S)-3-Hydroxyhexanoyl-CoA, Enoyl-CoA hydratase/isomerase family protein, SULFATE ION Authors: Bruning, J.B, Gao, N, Hernandez, E.D, Li, H, Dang, N, Hung, L.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2012-06-19 Release date: 2013-05-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure and mechanism of the prokaryotic enoyl CoA isomerase To be Published
4FOE	Crystal Structure of recombinant human Hexokinase type I with Mannose 6-Phosphate Descriptor: 6-O-phosphono-beta-D-mannopyranose, CITRIC ACID, Hexokinase-1, ... Authors: Shen, L, Honzatko, R.B. Deposit date: 2012-06-20 Release date: 2013-07-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Inhibitor Sites of Unequal Affinity Linked by Binding Synergism in Mutant Forms of Recombinant Human Hexokinase Type-I to be published
4FOG	Crystal Structure of Mtb ThyA in Complex with 5-Fluoro-dUMP and 5-methyltetrahydrofolic acid Descriptor: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Thymidylate synthase Authors: Reddy, M.C.M, Bruning, J.B, Harshbarger, W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2012-06-20 Release date: 2013-08-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: Insights into the selectivity and mode of inhibition To be Published

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