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3CFT

Crystal structure of human transthyretin in complex with 1-amino-5-naphthalene sulfonate

Summary for 3CFT
Entry DOI10.2210/pdb3cft/pdb
Related3CFM 3CFN 3CFQ
DescriptorTransthyretin, 5-aminonaphthalene-1-sulfonic acid (3 entities in total)
Functional Keywordshuman wild-type transthyretin, thyroxin, amyloid, familial amyloid polyneurophaty, disease mutation, glycoprotein, hormone, polymorphism, polyneuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight26592.77
Authors
Lima, L.-M.T.R.,Foguel, D.,Polikarpov, I. (deposition date: 2008-03-04, release date: 2009-03-03, Last modification date: 2023-08-30)
Primary citationLima, L.M.,Silva, V.D.,Palmieri, L.D.,Oliveira, M.C.,Foguel, D.,Polikarpov, I.
Identification of a novel ligand binding motif in the transthyretin channel.
Bioorg.Med.Chem., 18:100-110, 2010
Cited by
PubMed: 19954984
DOI: 10.1016/j.bmc.2009.11.025
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.87 Å)
Structure validation

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