3CFQ
Crystal structure of human wild-type transthyretin in complex with diclofenac
Summary for 3CFQ
Entry DOI | 10.2210/pdb3cfq/pdb |
Related | 1dvx 3CFM 3CFN 3CFT |
Descriptor | Transthyretin, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID (3 entities in total) |
Functional Keywords | transthyretin, thyroxin, familial amyloid polyneurophaty, disease mutation, glycoprotein, hormone, polymorphism, polyneuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 26515.32 |
Authors | Lima, L.-M.T.R.,Foguel, D.,Polikarpov, I. (deposition date: 2008-03-04, release date: 2009-03-03, Last modification date: 2023-08-30) |
Primary citation | Lima, L.M.,Silva, V.D.,Palmieri, L.D.,Oliveira, M.C.,Foguel, D.,Polikarpov, I. Identification of a novel ligand binding motif in the transthyretin channel. Bioorg.Med.Chem., 18:100-110, 2010 Cited by PubMed: 19954984DOI: 10.1016/j.bmc.2009.11.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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