3CFN
Crystal structure of human transthyretin in complex with 1-anilino-8-naphthalene sulfonate
Summary for 3CFN
Entry DOI | 10.2210/pdb3cfn/pdb |
Related | 3CFM 3CFQ 3CFT |
Descriptor | Transthyretin, 8-ANILINO-1-NAPHTHALENE SULFONATE (3 entities in total) |
Functional Keywords | human transthyretin, amyloid, familial amyloid polyneurophaty, 1, 8-2an, disease mutation, glycoprotein, hormone, polyneuropathy, retinol-binding, secreted, thyroid hormone, transport, vitamin a, transport protein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 26521.71 |
Authors | Lima, L.-M.T.R.,Foguel, D.,Polikarpov, I. (deposition date: 2008-03-04, release date: 2009-03-03, Last modification date: 2023-08-30) |
Primary citation | Lima, L.M.,Silva, V.D.,Palmieri, L.D.,Oliveira, M.C.,Foguel, D.,Polikarpov, I. Identification of a novel ligand binding motif in the transthyretin channel. Bioorg.Med.Chem., 18:100-110, 2010 Cited by PubMed: 19954984DOI: 10.1016/j.bmc.2009.11.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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