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4PWK
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BU of 4pwk by Molmil
Crystal structure of V30M mutant human transthyretin complexed with dihydroguaiaretic acid
Descriptor: 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol), Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-03-20
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
4QRF
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BU of 4qrf by Molmil
Crystal structure of V30M mutant human transthyretin complexed with caffeic acid phenethyl ester
Descriptor: 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Transthyretin
Authors:Yokoyama, T, Kosaka, Y, Mizuguchi, M.
Deposit date:2014-06-30
Release date:2014-11-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
2QPF
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BU of 2qpf by Molmil
Crystal Structure of Mouse Transthyretin
Descriptor: Transthyretin
Authors:Reixach, N, Foss, T.R, Santelli, E, Pascual, J, Kelly, J.W, Buxbaum, J.N.
Deposit date:2007-07-23
Release date:2007-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Human-Murine Transthyretin Heterotetramers Are Kinetically Stable and Non-amyloidogenic: A LESSON IN THE GENERATION OF TRANSGENIC MODELS OF DISEASES INVOLVING OLIGOMERIC PROTEINS.
J.Biol.Chem., 283, 2008
1ETA
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BU of 1eta by Molmil
THE X-RAY CRYSTAL STRUCTURE REFINEMENTS OF NORMAL HUMAN TRANSTHYRETIN AND THE AMYLOIDOGENIC VAL 30-->MET VARIANT TO 1.7 ANGSTROMS RESOLUTION
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN
Authors:Braden, B.C, Steinrauf, L.K, Hamilton, J.A.
Deposit date:1993-05-12
Release date:1995-01-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution.
J.Biol.Chem., 268, 1993
1FHN
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BU of 1fhn by Molmil
TRANSTHYRETIN STABILITY AS A KEY FACTOR IN AMYLOIDOGENESIS
Descriptor: Transthyretin
Authors:Sebastiao, M.P.
Deposit date:2000-08-02
Release date:2001-07-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.
J.Mol.Biol., 306, 2001
1FH2
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BU of 1fh2 by Molmil
TRANSTHYRETIN STABILITY AS A KEY FACTOR IN AMYLOIDOGENESIS
Descriptor: TRANSTHYRETIN
Authors:Sebastiao, M.P.
Deposit date:2000-07-31
Release date:2001-07-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.
J.Mol.Biol., 306, 2001
1MA9
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BU of 1ma9 by Molmil
Crystal structure of the complex of human vitamin D binding protein and rabbit muscle actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, Alpha Skeletal Muscle, ...
Authors:Verboven, C, Bogaerts, I, Waelkens, E, Rabijns, A, Van Baelen, H, Bouillon, R, De Ranter, C.
Deposit date:2002-08-02
Release date:2003-02-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Actin-DBP: the perfect structural fit?
Acta Crystallogr.,Sect.D, 59, 2003
2MOV
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BU of 2mov by Molmil
Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs.
Descriptor: Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine
Authors:Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R.
Deposit date:2014-05-05
Release date:2014-06-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs.
Biochemistry, 53, 2014
1IE4
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BU of 1ie4 by Molmil
RAT TRANSTHYRETIN COMPLEX WITH THYROXINE (T4)
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN
Authors:Wojtczak, A.
Deposit date:2001-04-06
Release date:2002-04-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 A resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites.
Acta Crystallogr.,Sect.D, 57, 2001
2WQA
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BU of 2wqa by Molmil
Complex of TTR and RBP4 and Oleic Acid
Descriptor: OLEIC ACID, RETINOL-BINDING PROTEIN 4, SULFATE ION, ...
Authors:Nanao, M, Mercer, D, Nguyen, L, Buckley, D, Stout, T.J.
Deposit date:2009-08-14
Release date:2010-09-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of Rbp4 Bound to Linoleic Acid and Ttr
To be Published
8I00
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BU of 8i00 by Molmil
Crystal structure of A97S transthyretin
Descriptor: Transthyretin
Authors:Agrawal, S, Yu, T.-Y.
Deposit date:2023-01-10
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and dynamics of pathogenic transthyretin variant A97S
To Be Published
8I0O
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BU of 8i0o by Molmil
Crystal structure of Transthyretin variant A97S in monomeric form
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Transthyretin
Authors:Agrawal, S, Yu, T.-Y.
Deposit date:2023-01-11
Release date:2024-01-17
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure and dynamics of Transthyretin pathogenic variant A97S
To Be Published
2D3I
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BU of 2d3i by Molmil
Crystal Structure of Aluminum-Bound Ovotransferrin at 2.15 Angstrom Resolution
Descriptor: ALUMINUM ION, BICARBONATE ION, Ovotransferrin
Authors:Mizutani, K, Mikami, B, Aibara, S, Hirose, M.
Deposit date:2005-09-28
Release date:2005-11-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of aluminium-bound ovotransferrin at 2.15 Angstroms resolution.
Acta Crystallogr.,Sect.D, 61, 2005
4PVM
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BU of 4pvm by Molmil
Neutron structure of human transthyretin (TTR) at room temperature to 2.0A resolution (Laue)
Descriptor: Transthyretin
Authors:Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
Deposit date:2014-03-18
Release date:2014-11-12
Last modified:2024-03-20
Method:NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
Cite:Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
4PVL
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BU of 4pvl by Molmil
X-ray structure of human transthyretin (TTR) at room temperature to 1.9A resolution
Descriptor: Transthyretin
Authors:Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
Deposit date:2014-03-18
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
4PMF
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BU of 4pmf by Molmil
Human transthyretin (TTR) complexed with curcumin
Descriptor: (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, 1,2-ETHANEDIOL, SODIUM ION, ...
Authors:Stura, E.A, Ciccone, L.
Deposit date:2014-05-21
Release date:2014-10-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures.
N Biotechnol, 32, 2014
4PVN
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BU of 4pvn by Molmil
Neutron structure of human transthyretin (TTR) at room temperature to 2.3A resolution (monochromatic)
Descriptor: Transthyretin
Authors:Fisher, S.J, Blakeley, M.P, Haupt, M, Mason, S.A, Cooper, J.B, Mitchell, E.P, Forsyth, V.T.
Deposit date:2014-03-18
Release date:2014-11-12
Last modified:2024-03-20
Method:NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION
Cite:Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein
IUCrJ, 1, 2014
1RVS
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BU of 1rvs by Molmil
STRUCTURE OF TRANSTHYRETIN IN AMYLOID FIBRILS DETERMINED BY SOLID-STATE MAGIC ANGLE SPINNING NMR
Descriptor: Transthyretin
Authors:Jaroniec, C.P, Macphee, C.E, Bajaj, V.S, Mcmahon, M.T, Dobson, C.M, Griffin, R.G.
Deposit date:2003-12-14
Release date:2004-01-20
Last modified:2024-05-01
Method:SOLID-STATE NMR
Cite:High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 101, 2004
1JL4
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BU of 1jl4 by Molmil
CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE
Descriptor: H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ...
Authors:Wang, J.-H, Meijers, R, Reinherz, E.L.
Deposit date:2001-07-15
Release date:2001-09-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule.
Proc.Natl.Acad.Sci.USA, 98, 2001

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