1IE4

RAT TRANSTHYRETIN COMPLEX WITH THYROXINE (T4)

Summary for 1IE4

• Entry DOI: 10.2210/pdb1ie4/pdb
• Related: 1GKE 1ICT 2ROX
• Descriptor: TRANSTHYRETIN, 3,5,3',5'-TETRAIODO-L-THYRONINE (3 entities in total)
• Functional Keywords: transport protein, transport of thyroid hormones, rat transthyretin, prealbumin, thyroxine complex
• Biological source: Rattus norvegicus (Norway rat)
• Cellular location: Secreted : P02767
• Total number of polymer chains: 4
• Total formula weight: 56010.33

Authors

Wojtczak, A. (deposition date: 2001-04-06, release date: 2002-04-10, Last modification date: 2023-11-15)

• Primary citation: Wojtczak, A.,Cody, V.,Luft, J.R.,Pangborn, W.; Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 A resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites.; Acta Crystallogr.,Sect.D, 57:1061-1070, 2001; PubMed: 11468389; DOI: 10.1107/S0907444901007235

Experimental method

X-RAY DIFFRACTION (2.5 Å)