2MOV
Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs.
Summary for 2MOV
Entry DOI | 10.2210/pdb2mov/pdb |
NMR Information | BMRB: 19953 |
Descriptor | Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine (2 entities in total) |
Functional Keywords | protein/ligand, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: Q15109 |
Total number of polymer chains | 1 |
Total formula weight | 11799.57 |
Authors | Shekhtman, A.,Xue, J.,Ray, R.,Singer, D.,Bohme, D.,Burz, D.S.,Rai, V.,Hoffman, R. (deposition date: 2014-05-05, release date: 2014-06-25, Last modification date: 2023-06-14) |
Primary citation | Xue, J.,Ray, R.,Singer, D.,Bohme, D.,Burz, D.S.,Rai, V.,Hoffmann, R.,Shekhtman, A. The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs. Biochemistry, 53:3327-3335, 2014 Cited by PubMed: 24824951DOI: 10.1021/bi500046t PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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