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6CW7
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BU of 6cw7 by Molmil
E. coli DHFR product complex with (6S)-5,6,7,8-TETRAHYDROFOLATE
Descriptor: (6S)-5,6,7,8-TETRAHYDROFOLATE, CHLORIDE ION, Dihydrofolate reductase, ...
Authors:Cao, H, Rodrigues, J, Benach, J, Frommelt, A, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J.
Deposit date:2018-03-30
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
Commun Biol, 1, 2018
6CYV
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BU of 6cyv by Molmil
E. coli DHFR ternary complex with NADP and dihydrofolate
Descriptor: DIHYDROFOLIC ACID, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cao, H, Rodrigues, J, Benach, J, Frommelt, A, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J.
Deposit date:2018-04-06
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
Commun Biol, 1, 2018
3KW0
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BU of 3kw0 by Molmil
Crystal structure of Cysteine peptidase (NP_982244.1) from BACILLUS CEREUS ATCC 10987 at 2.50 A resolution
Descriptor: CHLORIDE ION, Cysteine peptidase, LYSINE
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2009-11-30
Release date:2009-12-15
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites.
Plos One, 6, 2011
6CXK
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BU of 6cxk by Molmil
E. coli DHFR substrate complex with Dihydrofolate
Descriptor: CHLORIDE ION, DIHYDROFOLIC ACID, Dihydrofolate reductase, ...
Authors:Cao, H, Rodrigues, J, Benach, J, Frommelt, A, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J.
Deposit date:2018-04-03
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.108 Å)
Cite:The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
Commun Biol, 1, 2018
5E4T
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BU of 5e4t by Molmil
Acetylcholinesterase Methylene Blue with PEG
Descriptor: 1,2-ETHANEDIOL, 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, Acetylcholinesterase, ...
Authors:Dym, O.
Deposit date:2015-10-07
Release date:2016-03-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex.
Protein Sci., 25, 2016
6D4E
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BU of 6d4e by Molmil
Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG1.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Fc Fragment of IgG1
Authors:Gohain, N, Tolbert, W.D, Pazgier, M.
Deposit date:2018-04-18
Release date:2019-05-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Mabs, 11, 2019
5L9D
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BU of 5l9d by Molmil
AFAMIN ANTIBODY FRAGMENT, N14 FAB, L1- GLYCOSYLATED, CRYSTAL FORM I, parsimonious model
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Rupp, B, Naschberger, A.
Deposit date:2016-06-10
Release date:2016-08-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Acta Crystallogr D Struct Biol, 72, 2016
5L7X
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BU of 5l7x by Molmil
Afamin antibody fragment, N14 Fab, L1- glycosylated, crystal form II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Mouse Antibody Fab Fragment, ...
Authors:Rupp, B, Naschberger, A.
Deposit date:2016-06-04
Release date:2016-07-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Acta Crystallogr D Struct Biol, 72, 2016
7Z6Z
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BU of 7z6z by Molmil
Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with fosinoprilat
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cozier, G.E, Acharya, K.R.
Deposit date:2022-03-14
Release date:2022-06-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat.
Febs J., 289, 2022
7Z70
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BU of 7z70 by Molmil
Crystal structure of Angiotensin-1 converting enzyme C-domain in complex with fosinoprilat
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Cozier, G.E, Acharya, K.R.
Deposit date:2022-03-14
Release date:2022-06-22
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat.
Febs J., 289, 2022
5HVW
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BU of 5hvw by Molmil
Monomeric IgG4 Fc
Descriptor: GLYCEROL, Ig gamma-4 chain C region, ZINC ION, ...
Authors:Oganesyan, V.Y, Shan, L, Dall'Acqua, W.F.
Deposit date:2016-01-28
Release date:2016-08-17
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Generation and Characterization of an IgG4 Monomeric Fc Platform.
Plos One, 11, 2016
6CQA
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BU of 6cqa by Molmil
E. coli DHFR complex with inhibitor AMPQD
Descriptor: 7-[(3-aminophenyl)methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, SULFATE ION
Authors:Cao, H, Rodrigues, J, Benach, J, Wasserman, S, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J.
Deposit date:2018-03-14
Release date:2019-01-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release.
Commun Biol, 1, 2018
8GW0
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BU of 8gw0 by Molmil
Crystal structure of the human dihydroorotase domain in complex with malic acid
Descriptor: (2S)-2-hydroxybutanedioic acid, CAD protein, ZINC ION
Authors:Yang, P.C, Liu, H.W, Huang, H.Y, Huang, C.Y.
Deposit date:2022-09-16
Release date:2023-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13, 2023
7DFQ
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BU of 7dfq by Molmil
Crystal Structure of a novel 4-O-alpha-L-rhamnosyl-beta-D-glucuronidase from Fusarium oxysporum 12S, ligand-free form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-alpha-L-rhamnosyl-beta-D-glucuronidase
Authors:Kondo, T, Arakawa, T, Fushinobu, S, Sakamoto, T.
Deposit date:2020-11-09
Release date:2021-03-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Biochemical and structural characterization of a novel 4-O-alpha-l-rhamnosyl-beta-d-glucuronidase from Fusarium oxysporum.
Febs J., 288, 2021
8GVZ
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BU of 8gvz by Molmil
Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil
Descriptor: 5-FLUOROURACIL, CAD protein, ZINC ION
Authors:Liu, H.W, Yang, P.C, Huang, H.Y, Huang, C.Y.
Deposit date:2022-09-16
Release date:2023-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13, 2023
6RFZ
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BU of 6rfz by Molmil
Photorhabdus laumondii lectin PLL2 in complex with D-glucose
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ...
Authors:Houser, J, Fujdiarova, E, Wimmerova, M.
Deposit date:2019-04-16
Release date:2020-07-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Heptabladed beta-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Febs J., 288, 2021
6RG1
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BU of 6rg1 by Molmil
Photorhabdus laumondii lectin PLL2 in complex with L-rhamnose
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ...
Authors:Houser, J, Fujdiarova, E, Wimmerova, M.
Deposit date:2019-04-16
Release date:2020-07-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Heptabladed beta-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Febs J., 288, 2021
7P8O
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BU of 7p8o by Molmil
Crystal structure of D-aminoacid transaminase from Haliscomenobacter hydrossis in its intermediate form
Descriptor: Aminotransferase class IV, MAGNESIUM ION, SULFATE ION
Authors:Matyuta, I.O, Boyko, K.M, Bakunova, A.K, Nikolaeva, A.Y, Rakitina, T.V, Bezsudnova, E.Y, Popov, V.O.
Deposit date:2021-07-23
Release date:2022-08-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Incorporation of pyridoxal-5'-phosphate into the apoenzyme: A structural study of D-amino acid transaminase from Haliscomenobacter hydrossis.
Biochim Biophys Acta Proteins Proteom, 1873, 2024
5LGH
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BU of 5lgh by Molmil
Afamin antibody fragment, N14 Fab, L1- glycosilated, crystal form II, same as 5L7X, but isomorphous setting indexed same as 5L88, 5L9D
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, MOUSE ANTIBODY FAB FRAGMENT, ...
Authors:Rupp, B, Naschberger, A.
Deposit date:2016-07-07
Release date:2016-08-03
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The N14 anti-afamin antibody Fab: a rare VL1 CDR glycosylation, crystallographic re-sequencing, molecular plasticity and conservative versus enthusiastic modelling.
Acta Crystallogr D Struct Biol, 72, 2016
6M13
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BU of 6m13 by Molmil
Crystal structure of Rnase L in complex with Toceranib
Descriptor: 5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-(2-pyrrolidin-1-ylethyl)-1H-pyrrole-3-carboxamide, PHOSPHATE ION, Ribonuclease L, ...
Authors:Tang, J, Huang, H.
Deposit date:2020-02-24
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Sunitinib inhibits RNase L by destabilizing its active dimer conformation.
Biochem.J., 477, 2020
3N2X
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BU of 3n2x by Molmil
Crystal structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12 in complex with pyruvate
Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein yagE
Authors:Bhaskar, V, Kumar, P.M, Manicka, S, Krishnaswamy, S.
Deposit date:2010-05-19
Release date:2011-04-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis.
Proteins, 79, 2011
6D4I
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BU of 6d4i by Molmil
Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc fragment of IgG2
Authors:Gohain, N, Tolbert, W.D, Pazgier, M.
Deposit date:2018-04-18
Release date:2019-05-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Mabs, 11, 2019
3NEV
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BU of 3nev by Molmil
Crystal structure of YagE, a prophage protein from E. coli K12 in complex with KDGal
Descriptor: 1,2-ETHANEDIOL, 3-DEOXY-D-LYXO-HEXONIC ACID, Uncharacterized protein yagE
Authors:Bhaskar, V, Kumar, P.M, Manicka, S, Krishnaswamy, S.
Deposit date:2010-06-09
Release date:2011-04-13
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Identification of biochemical and putative biological role of a xenolog from Escherichia coli using structural analysis.
Proteins, 79, 2011
6LR9
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BU of 6lr9 by Molmil
HSP90 in complex with Debio0932
Descriptor: 2-[[6-(dimethylamino)-1,3-benzodioxol-5-yl]sulfanyl]-1-[2-(2,2-dimethylpropylamino)ethyl]imidazo[4,5-c]pyridin-4-amine, GLYCEROL, Heat shock protein HSP 90-alpha
Authors:Cao, H.L.
Deposit date:2020-01-15
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Complex crystal structure determination and anti-non-small-cell lung cancer activity of the Hsp90 N inhibitor Debio0932.
Acta Crystallogr D Struct Biol, 77, 2021
6LTK
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BU of 6ltk by Molmil
HSP90 in complex with SNX-2112
Descriptor: 4-[6,6-dimethyl-4-oxidanylidene-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-oxidanylcyclohexyl)amino]benzamide, Heat shock protein HSP 90-alpha
Authors:Cao, H.L.
Deposit date:2020-01-22
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Complex Crystal Structure Determination and in vitro Anti-non-small Cell Lung Cancer Activity of Hsp90 N Inhibitor SNX-2112.
Front Cell Dev Biol, 9, 2021

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