7Z6Z

Crystal structure of Angiotensin-1 converting enzyme N-domain in complex with fosinoprilat

Summary for 7Z6Z

• Entry DOI: 10.2210/pdb7z6z/pdb
• Descriptor: Angiotensin-converting enzyme, soluble form, ACETATE ION, 1,2-ETHANEDIOL, ... (17 entities in total)
• Functional Keywords: angiotensin-1 converting enzyme, fosinoprilat, fosinopril, metalloprotease, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 151909.36

Authors

Cozier, G.E.,Acharya, K.R. (deposition date: 2022-03-14, release date: 2022-06-22, Last modification date: 2024-01-31)

• Primary citation: Cozier, G.E.,Newby, E.C.,Schwager, S.L.U.,Isaac, R.E.,Sturrock, E.D.,Acharya, K.R.; Structural basis for the inhibition of human angiotensin-1 converting enzyme by fosinoprilat.; Febs J., 289:6659-6671, 2022; PubMed: 35653492; DOI: 10.1111/febs.16543

Experimental method

X-RAY DIFFRACTION (1.75 Å)