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2HDD
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ENGRAILED HOMEODOMAIN Q50K VARIANT DNA COMPLEX
Descriptor: DNA (5'-D(*AP*TP*CP*CP*GP*GP*GP*GP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*CP*CP*C P*CP*GP*GP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN Q50K)
Authors:Tucker-Kellogg, L, Rould, M.A, Chambers, K.A, Ades, S.E, Sauer, R.T, Pabo, C.O.
Deposit date:1998-02-10
Release date:1998-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engrailed (Gln50-->Lys) homeodomain-DNA complex at 1.9 A resolution: structural basis for enhanced affinity and altered specificity.
Structure, 5, 1997
2HDE
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Solution Structure of Human SAP18
Descriptor: Histone deacetylase complex subunit SAP18
Authors:McCallum, S.A, Yin, J.P, Pan, B, Fairbrother, W.J.
Deposit date:2006-06-20
Release date:2007-04-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of SAP18: a ubiquitin fold in histone deacetylase complex assembly.
Biochemistry, 45, 2006
2HDF
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Crystal structure of the Colicin I receptor Cir from E.coli
Descriptor: Colicin I receptor, N-OCTYL-2-HYDROXYETHYL SULFOXIDE, STRONTIUM ION
Authors:Buchanan, S.K, Esser, L, Lukacik, P.
Deposit date:2006-06-20
Release date:2007-05-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import.
Embo J., 26, 2007
2HDH
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BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM
Descriptor: L-3-HYDROXYACYL COA DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Barycki, J.J, Bratt, J.M, Banaszak, L.J.
Deposit date:1998-12-04
Release date:1999-05-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism.
Biochemistry, 38, 1999
2HDI
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Crystal structure of the Colicin I receptor Cir from E.coli in complex with receptor binding domain of Colicin Ia.
Descriptor: Colicin I receptor, Colicin-Ia, LAURYL DIMETHYLAMINE-N-OXIDE
Authors:Buchanan, S.K, Esser, L, Lukacik, P.
Deposit date:2006-06-20
Release date:2007-05-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import.
Embo J., 26, 2007
2HDJ
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Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H)
Descriptor: 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member C2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Faucher, F, Pereira de Jesus-Tran, K, Cantin, L, Luu-the, V, Labrie, F, Breton, R.
Deposit date:2006-06-20
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme.
J.Mol.Biol., 364, 2006
2HDK
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Crystal Structure of Cys315Ala-Cys318Ala Mutant of Human Mitochondrial Branched Chain Aminotransferase
Descriptor: 2-OXO-4-METHYLPENTANOIC ACID, ACETIC ACID, Branched-chain-amino-acid aminotransferase, ...
Authors:Yennawar, N.H, Hutson, S.M.
Deposit date:2006-06-20
Release date:2006-10-24
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human Mitochondrial Branched Chain Aminotransferase Isozyme: STRUCTURAL ROLE OF THE CXXC CENTER IN CATALYSIS.
J.Biol.Chem., 281, 2006
2HDL
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Solution structure of Brak/CXCL14
Descriptor: Small inducible cytokine B14
Authors:Peterson, F.C, Thorpe, J.A, Harder, A.G, Volkman, B.F, Schwarze, S.R.
Deposit date:2006-06-20
Release date:2006-10-24
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structural Determinants Involved in the Regulation of CXCL14/BRAK Expression by the 26 S Proteasome.
J.Mol.Biol., 363, 2006
2HDM
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Solution structure of V21C/V59C Lymphotactin/XCL1
Descriptor: Lymphotactin
Authors:Volkman, B.F, Tuinstra, R.L, Peterson, F.C, Elgin, E.S.
Deposit date:2006-06-20
Release date:2007-05-01
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity
Biochemistry, 46, 2007
2HDN
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Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution
Descriptor: Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
Deposit date:2006-06-20
Release date:2006-10-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
2HDO
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Crystal structure of putative phosphoglycolate phosphatase (np_784602.1) from Lactobacillus plantarum at 1.50 A resolution
Descriptor: PHOSPHATE ION, Phosphoglycolate phosphatase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-06-20
Release date:2006-08-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of putative phosphoglycolate phosphatase (np_784602.1) from Lactobacillus plantarum at 1.50 A resolution
To be published
2HDP
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Solution Structure of Hdm2 RING Finger Domain
Descriptor: Ubiquitin-protein ligase E3 Mdm2, ZINC ION
Authors:Kostic, M, Matt, T, Yamout-Martinez, M, Dyson, H.J, Wright, P.E.
Deposit date:2006-06-20
Release date:2006-11-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.
J.Mol.Biol., 363, 2006
2HDQ
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AmpC beta-lactamase in complex with 2-carboxythiophene
Descriptor: Beta-lactamase, THIOPHENE-2-CARBOXYLIC ACID
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDR
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BU of 2hdr by Molmil
AmpC beta-lactamase in complex with 4-Amino-3-hydroxybenzoic acid
Descriptor: 4-AMINO-3-HYDROXYBENZOIC ACID, Beta-lactamase, PHOSPHATE ION
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDS
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BU of 2hds by Molmil
AmpC beta-lactamase in complex with 4-Methanesulfonylamino benzoic acid
Descriptor: 4-[(METHYLSULFONYL)AMINO]BENZOIC ACID, Beta-lactamase, PHOSPHATE ION, ...
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDU
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BU of 2hdu by Molmil
AmpC beta-lactamase in complex with 2-acetamidothiophene-3-carboxylic acid
Descriptor: 2-(ACETYLAMINO)THIOPHENE-3-CARBOXYLIC ACID, Beta-lactamase, PHOSPHATE ION, ...
Authors:Babaoglu, K, Shoichet, B.K.
Deposit date:2006-06-20
Release date:2006-11-07
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Deconstructing fragment-based inhibitor discovery
Nat.Chem.Biol., 2, 2006
2HDV
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BU of 2hdv by Molmil
Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B
Descriptor: SH2-B PH domain containing signaling mediator 1 gamma isoform
Authors:Hu, J, Hubbard, S.R.
Deposit date:2006-06-20
Release date:2006-08-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HDW
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BU of 2hdw by Molmil
Crystal structure of hypothetical protein PA2218 from Pseudomonas Aeruginosa
Descriptor: Hypothetical protein PA2218
Authors:Fedorov, A.A, Fedorov, E.V, Ramagopal, U, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-21
Release date:2006-11-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of hypothetical protein PA2218 from Pseudomonas Aeruginosa
To be Published
2HDX
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Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
Descriptor: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform
Authors:Hu, J, Hubbard, S.R.
Deposit date:2006-06-21
Release date:2006-08-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HDZ
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BU of 2hdz by Molmil
Crystal Structure Analysis of the UBF HMG box5
Descriptor: Nucleolar transcription factor 1
Authors:Rong, H, Teng, M.K, Niu, L.W.
Deposit date:2006-06-21
Release date:2007-06-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human upstream binding factor HMG box 5 and site for binding of the cell-cycle regulatory factor TAF1
Acta Crystallogr.,Sect.D, 63, 2007
2HE0
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BU of 2he0 by Molmil
Crystal structure of a human Notch1 ankyrin domain mutant
Descriptor: 1,2-ETHANEDIOL, Notch1 preproprotein variant
Authors:Gupta, D, Ehebauer, M.T, Chirgadze, D.Y, Martinez Arias, A, Blundell, T.L.
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a human Notch1 ankyrin domain mutant
TO BE PUBLISHED
2HE2
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Crystal structure of the 3rd PDZ domain of human discs large homologue 2, DLG2
Descriptor: Discs large homolog 2
Authors:Turnbull, A.P, Phillips, C, Berridge, G, Savitsky, P, Smee, C.E.A, Papagrigoriou, E, Debreczeni, J, Gorrec, F, Elkins, J.M, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2HE3
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BU of 2he3 by Molmil
Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
Descriptor: CHLORIDE ION, Glutathione peroxidase 2
Authors:Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
2HE4
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The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif
Descriptor: 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Authors:Papagrigoriou, E, Elkins, J.M, Berridge, G, Gileady, O, Colebrook, S, Gileadi, C, Salah, E, Savitsky, P, Pantic, N, Gorrec, F, Bunkoczi, G, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Doyle, D.A, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2HE5
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Crystal structure of 17alpha-hydroxysteroid dehydrogenase in binary complex with NADP(H) in an open conformation
Descriptor: ACETATE ION, Aldo-keto reductase family 1, member C21, ...
Authors:Faucher, F, Pereira de Jesus-Tran, K, Cantin, L, Luu-the, V, Labrie, F, Breton, R.
Deposit date:2006-06-21
Release date:2006-12-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme.
J.Mol.Biol., 364, 2006

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