2HE4
The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif
Summary for 2HE4
Entry DOI | 10.2210/pdb2he4/pdb |
Descriptor | Na(+)/H(+) exchange regulatory cofactor NHE-RF2, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | phosphorylation, structural genomics, structural genomics consortium, sgc, unknown function |
Biological source | Homo sapiens (human) |
Cellular location | Endomembrane system; Peripheral membrane protein: Q15599 |
Total number of polymer chains | 1 |
Total formula weight | 9993.38 |
Authors | Papagrigoriou, E.,Elkins, J.M.,Berridge, G.,Gileady, O.,Colebrook, S.,Gileadi, C.,Salah, E.,Savitsky, P.,Pantic, N.,Gorrec, F.,Bunkoczi, G.,Weigelt, J.,Arrowsmith, C.,Sundstrom, M.,Edwards, A.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2006-06-21, release date: 2006-07-18, Last modification date: 2023-08-30) |
Primary citation | Elkins, J.M.,Papagrigoriou, E.,Berridge, G.,Yang, X.,Phillips, C.,Gileadi, C.,Savitsky, P.,Doyle, D.A. Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. Protein Sci., 16:683-694, 2007 Cited by PubMed: 17384233DOI: 10.1110/ps.062657507 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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