2HDQ

AmpC beta-lactamase in complex with 2-carboxythiophene

Summary for 2HDQ

Entry DOI	10.2210/pdb2hdq/pdb
Related	2HDR 2HDS 2HDU
Descriptor	Beta-lactamase, THIOPHENE-2-CARBOXYLIC ACID (3 entities in total)
Functional Keywords	fragment-based beta-lactamase ampc drug design, hydrolase
Biological source	Escherichia coli K12
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	80713.63
Authors	Babaoglu, K.,Shoichet, B.K. (deposition date: 2006-06-20, release date: 2006-11-07, Last modification date: 2023-08-30)
Primary citation	Babaoglu, K.,Shoichet, B.K. Deconstructing fragment-based inhibitor discovery Nat.Chem.Biol., 2:720-723, 2006 Cited by PubMed: 17072304 DOI: 10.1038/nchembio831 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation