2HDJ

Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(H)

Summary for 2HDJ

Entry DOI	10.2210/pdb2hdj/pdb
Descriptor	Aldo-keto reductase family 1 member C2, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	human 3alphahds3, aldo-keto reductase, nadph, akr, akr1c2, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm (Potential): P52895
Total number of polymer chains	2
Total formula weight	75820.03
Authors	Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-the, V.,Labrie, F.,Breton, R. (deposition date: 2006-06-20, release date: 2006-12-05, Last modification date: 2023-08-30)
Primary citation	Faucher, F.,Pereira de Jesus-Tran, K.,Cantin, L.,Luu-The, V.,Labrie, F.,Breton, R. Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme. J.Mol.Biol., 364:747-763, 2006 Cited by PubMed: 17034817 DOI: 10.1016/j.jmb.2006.09.030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation