PDB: 79225 resultsInfo pagesStatus searchChemie searchBIRD

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6UPZ	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.1 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UPY	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ3	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.47 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UPX	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ0	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.56 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ2	RNA polymerase II elongation complex with dG in state 1 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.2 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ1	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6 Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Oh, J, Wang, D. Deposit date: 2019-10-18 Release date: 2020-06-10 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.6 Å) Cite: RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
9IMB	The crystal structure of human m5C methyltransferase NSUN6 bound to its S-adenosyl-L-methionine analog and a NECTIN-2 3'-UTR RNA substrate Descriptor: RNA (5'-R(*GP*CP*CP*CP*UP*CP*UP*UP*CP*AP*UP*CP*UP*CP*CP*AP*AP*AP*GP*AP*GP*GP*GP*C)-3'), SINEFUNGIN, tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 Authors: Lv, M.Q, Zhong, F.M, Pu, T. Deposit date: 2024-07-02 Release date: 2025-01-08 Last modified: 2025-03-19 Method: X-RAY DIFFRACTION (2.9 Å) Cite: NSUN6 inhibitor discovery guided by its mRNA substrate bound crystal structure. Structure, 33, 2025
5XWG	Crystal structure of a novel RNA motif that allows for precise positioning of a metal ion Descriptor: RNA (5'-R(P*CP*GP*CP*UP*(5BU)P*CP*GP*AP*AP*AP*AP*AP*GP*UP*C)-3'), STRONTIUM ION Authors: Kanazawa, H, Kondo, J. Deposit date: 2017-06-29 Release date: 2017-10-11 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (3.002 Å) Cite: Crystal structure of a novel RNA motif that allows for precise positioning of a single metal ion. J. Inorg. Biochem., 176, 2017
1A9N	CRYSTAL STRUCTURE OF THE SPLICEOSOMAL U2B''-U2A' PROTEIN COMPLEX BOUND TO A FRAGMENT OF U2 SMALL NUCLEAR RNA Descriptor: RNA (5'-R(*CP*CP*UP*GP*GP*UP*AP*UP*UP*GP*CP*AP*GP*UP*AP*CP*CP*UP*CP*CP*AP*GP* GP*U)-3'), SPLICEOSOMAL U2B'', U2A' Authors: Price, S.R, Evans, P.R, Nagai, K. Deposit date: 1998-04-08 Release date: 1998-09-23 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA. Nature, 394, 1998
6HKO	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-07 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6HLR	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
5XON	RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... Authors: Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. Deposit date: 2017-05-29 Release date: 2017-08-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.83 Å) Cite: Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
6N4O	Human Argonaute2-miR-122 bound to a seed and supplementary paired target Descriptor: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-11-19 Release date: 2019-05-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.899 Å) Cite: Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2. Embo J., 38, 2019
5G5L	RNA polymerase I-Rrn3 complex at 4.8 A resolution Descriptor: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... Authors: Engel, C, Plitzko, J, Cramer, P. Deposit date: 2016-05-26 Release date: 2016-07-27 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution Nat.Commun., 7, 2016
8RZF	RNase W from Sulfolobus acidocaldarius Descriptor: MAGNESIUM ION, Probable ribonuclease FAU-1 Authors: Vayssieres, M, Blaud, M, Leulliot, N. Deposit date: 2024-02-12 Release date: 2024-11-06 Last modified: 2024-12-04 Method: X-RAY DIFFRACTION (2.04 Å) Cite: RNase W, a conserved ribonuclease family with a novel active site. Nucleic Acids Res., 52, 2024
7ZWD	Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. Deposit date: 2022-05-19 Release date: 2022-11-30 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7ZX7	Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. Deposit date: 2022-05-20 Release date: 2022-11-30 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
7ZX8	Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. Deposit date: 2022-05-20 Release date: 2022-12-07 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
6UFM	Cocrystal Structure of the Nocardia farcinica ileS T-box riboswitch in complex with its cognate tRNA Descriptor: RNA (77-MER), RNA (98-MER), SULFATE ION Authors: Suddala, K.C, Zhang, J. Deposit date: 2019-09-24 Release date: 2019-12-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.82 Å) Cite: High-affinity recognition of specific tRNAs by an mRNA anticodon-binding groove. Nat.Struct.Mol.Biol., 26, 2019
9II7	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome containing histone variant H2A.B Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... Authors: Akatsu, M, Kujirai, T, Rina, H, Ehara, H, Takizawa, Y, Sekine, S, Kurumizaka, H. Deposit date: 2024-06-19 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural basis of RNAPII transcription on the nucleosome containing histone variant H2A.B. Embo J., 2025
6HLQ	Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... Authors: Tafur, L, Sadian, Y, Weis, F, Muller, C.W. Deposit date: 2018-09-11 Release date: 2019-04-03 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
1BRS	PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION Descriptor: BARNASE, BARSTAR Authors: Buckle, A.M, Schreiber, G, Fersht, A.R. Deposit date: 1994-03-11 Release date: 1994-06-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution. Biochemistry, 33, 1994
7DN3	Structure of Human RNA Polymerase III elongation complex Descriptor: DNA (5'-D(P*TP*CP*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*TP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase III subunit RPC1, ... Authors: Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. Deposit date: 2020-12-08 Release date: 2021-03-17 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
4U8T	Crystal structure of YTH domain of Zygosaccharomyces rouxii MRB1 protein in complex with N6-Methyladenosine RNA Descriptor: RNA (5'-R(*AP*GP*GP*(6MZ)P*CP*AP*U)-3'), ZYRO0G01672p Authors: Luo, S, Tong, L. Deposit date: 2014-08-04 Release date: 2014-09-10 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain. Proc.Natl.Acad.Sci.USA, 111, 2014

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