6G8F
 
 | | Crystal structure of UTX complexed with GSK-J1 | | Descriptor: | 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Esposito, C, Sledz, P, Caflisch, A. | | Deposit date: | 2018-04-08 | | Release date: | 2018-10-10 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.043 Å) | | Cite: | In Silico Identification of JMJD3 Demethylase Inhibitors.
J Chem Inf Model, 58, 2018
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4MY9
 | | Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor C91 | | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, MALONATE ION, ... | | Authors: | Kim, Y, Makowska-Grzyska, M, Gu, M, Gorla, S.K, Hedstrom, L, Anderson, W.F, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-09-27 | | Release date: | 2014-06-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5893 Å) | | Cite: | Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor C91
To be Published
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6G8Z
 | | Structure of the pore domain of homomeric mLRRC8A volume-regulated anion channel at 3.66 A resolution | | Descriptor: | Volume-regulated anion channel subunit LRRC8A | | Authors: | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | | Deposit date: | 2018-04-10 | | Release date: | 2018-05-16 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
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8EYC
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4N78
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6G9U
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8EVL
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8EZL
 | | Pfs25 in complex with transmission-reducing antibody AS01-50 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ... | | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-11-01 | | Release date: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
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6FTE
 | | Crystal structure of an (R)-selective amine transaminase from Exophiala xenobiotica | | Descriptor: | ACETATE ION, Amine transaminase (fold IV), GLYCEROL, ... | | Authors: | Telzerow, A, Hakansson, M, Schurrmann, M, Schwab, H, Steiner, K. | | Deposit date: | 2018-02-21 | | Release date: | 2019-01-09 | | Last modified: | 2020-01-29 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Amine Transaminase from Exophiala xenobiotica - Crystal Structure and Engineering of a Fold IV Transaminase that Naturally Converts Biaryl Ketones
Acs Catalysis, 2018
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8F7K
 | | Thermoplasma acidophilum 20S proteasome - wild type bound to ZYA | | Descriptor: | N-[(benzyloxy)carbonyl]-L-tyrosyl-D-alanine, Proteasome subunit alpha, Proteasome subunit beta | | Authors: | Chuah, J, Smith, D. | | Deposit date: | 2022-11-18 | | Release date: | 2023-08-30 | | Method: | ELECTRON MICROSCOPY (1.94 Å) | | Cite: | High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation.
Commun Biol, 6, 2023
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8U8O
 | | Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, octamer-centered | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ... | | Authors: | Calise, S.J, Kollman, J.M. | | Deposit date: | 2023-09-18 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
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4KQA
 | | Crystal structure of the golgi casein kinase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NICKEL (II) ION, Protein H03A11.1, ... | | Authors: | Xiao, J. | | Deposit date: | 2013-05-14 | | Release date: | 2013-06-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.603 Å) | | Cite: | Crystal structure of the Golgi casein kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6GCD
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8F66
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4KRA
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8U8Y
 | | Human retinal variant phosphomimetic IMPDH1(546)-S477D filament bound by ATP, IMP, and NAD+, interface-centered | | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Calise, S.J, Kollman, J.M. | | Deposit date: | 2023-09-18 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
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7P37
 | | Streptomyces coelicolor ATP-loaded NrdR | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Transcriptional repressor NrdR, ZINC ION | | Authors: | Martinez-Carranza, M, Stenmark, P. | | Deposit date: | 2021-07-07 | | Release date: | 2022-05-11 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
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6FV2
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8UM6
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4KSL
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7P4G
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8FTE
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7P0O
 | | mitoNEET bound to M1 molecule | | Descriptor: | 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, 2-benzamido-4-[(2~{S})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 1, ... | | Authors: | Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R. | | Deposit date: | 2021-06-30 | | Release date: | 2022-05-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
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4K4G
 | | Ternary crystal structures of human DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND L-DCTP. | | Descriptor: | 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, ACETATE ION, CACODYLATE ION, ... | | Authors: | Vyas, R, Suo, Z. | | Deposit date: | 2013-04-12 | | Release date: | 2014-07-16 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase lambda.
Proc.Natl.Acad.Sci.USA, 111, 2014
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7P3Q
 | | Streptomyces coelicolor dATP/ATP-loaded NrdR octamer | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transcriptional repressor NrdR, ... | | Authors: | Martinez-Carranza, M, Stenmark, P. | | Deposit date: | 2021-07-08 | | Release date: | 2022-05-11 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
Nat Commun, 13, 2022
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