6FOE
 
 | | BaxB01 Fab fragment | | Descriptor: | Fab BaxB01 heavy chain, Fab BaxB01 light chain | | Authors: | Hollerweger, J, Schinagl, A, Kerschbaumer, R.J, Scheiflinger, F, Thiele, M, Goettig, P, Brandstetter, H. | | Deposit date: | 2018-02-07 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch.
Biochemistry, 57, 2018
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1AVU
 | | TRYPSIN INHIBITOR FROM SOYBEAN (STI) | | Descriptor: | TRYPSIN INHIBITOR | | Authors: | Song, H.K, Suh, S.W. | | Deposit date: | 1997-09-20 | | Release date: | 1998-10-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator.
J.Mol.Biol., 275, 1998
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1AVW
 | | COMPLEX PORCINE PANCREATIC TRYPSIN/SOYBEAN TRYPSIN INHIBITOR, ORTHORHOMBIC CRYSTAL FORM | | Descriptor: | CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR | | Authors: | Song, H.K, Suh, S.W. | | Deposit date: | 1997-09-21 | | Release date: | 1998-10-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator.
J.Mol.Biol., 275, 1998
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1AVX
 | | COMPLEX PORCINE PANCREATIC TRYPSIN/SOYBEAN TRYPSIN INHIBITOR, TETRAGONAL CRYSTAL FORM | | Descriptor: | CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR | | Authors: | Song, H.K, Suh, S.W. | | Deposit date: | 1997-09-21 | | Release date: | 1998-10-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator.
J.Mol.Biol., 275, 1998
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1ZDU
 | | The Crystal Structure of Human Liver Receptor Homologue-1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nuclear receptor coactivator 2, Orphan nuclear receptor NR5A2, ... | | Authors: | Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L. | | Deposit date: | 2005-04-14 | | Release date: | 2005-05-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Proc.Natl.Acad.Sci.USA, 102, 2005
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5L0S
 | | human POGLUT1 in complex with Factor VII EGF1 and UDP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Li, Z, Rini, J.M. | | Deposit date: | 2016-07-28 | | Release date: | 2017-08-09 | | Last modified: | 2021-03-24 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).
Nat Commun, 8, 2017
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5HGU
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8PKJ
 | | Cryo-EM structure of the nucleosome containing Nr5a2 motif at SHL+5.5 | | Descriptor: | DNA, Histone H2A, Histone H2B, ... | | Authors: | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | | Deposit date: | 2023-06-26 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.
Nat.Struct.Mol.Biol., 31, 2024
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2XB1
 | | Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ... | | Authors: | Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M. | | Deposit date: | 2010-04-01 | | Release date: | 2010-07-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010
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1XF0
 | | Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP | | Descriptor: | 4-ANDROSTENE-3-17-DIONE, ACETATE ION, Aldo-keto reductase family 1 member C3, ... | | Authors: | Qiu, W, Zhou, M, Labrie, F, Lin, S.-X. | | Deposit date: | 2004-09-13 | | Release date: | 2004-10-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues
Mol.Endocrinol., 18, 2004
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5DLQ
 | | Crystal structure of RanGTP-Exportin 4-eIF5A complex | | Descriptor: | Eukaryotic translation initiation factor 5A-1, Exportin-4, GTP-binding nuclear protein Ran, ... | | Authors: | Aksu, M, Trakhanov, S, Gorlich, D. | | Deposit date: | 2015-09-07 | | Release date: | 2016-06-22 | | Last modified: | 2016-06-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.
Nat Commun, 7, 2016
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3MLP
 | | Early B-cell Factor 1 (Ebf1) bound to DNA | | Descriptor: | CITRIC ACID, DNA (5'-D(*CP*TP*TP*TP*AP*TP*TP*CP*CP*CP*AP*TP*GP*GP*GP*AP*AP*TP*AP*AP*AP*G)-3'), Transcription factor COE1, ... | | Authors: | Treiber, N, Treiber, T, Zocher, G, Grosschedl, R. | | Deposit date: | 2010-04-17 | | Release date: | 2010-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Genes Dev., 24, 2010
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8HIA
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8HGA
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5VT2
 | | Crystal structure of growth differentiation factor | | Descriptor: | 1,2-ETHANEDIOL, Growth/differentiation factor 15 | | Authors: | Min, X, Wang, Z. | | Deposit date: | 2017-05-15 | | Release date: | 2017-11-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.
Sci Transl Med, 9, 2017
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4M7K
 | | Crystal structure of anti-tissue factor antibody 10H10 | | Descriptor: | 10H10 heavy chain, 10H10 light chain, ACETATE ION, ... | | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | Deposit date: | 2013-08-12 | | Release date: | 2014-03-26 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
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5NIR
 | | Crystal structure of collagen 2A vWC domain | | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Collagen alpha-1(II) chain, ... | | Authors: | Fischer, G, Blythe, E, Hyvonen, M. | | Deposit date: | 2017-03-27 | | Release date: | 2017-06-14 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2.
J. Biol. Chem., 292, 2017
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3MLN
 | | DNA binding domain of Early B-cell Factor 1 (Ebf1) bound to DNA (crystal form II) | | Descriptor: | DNA (5'-D(*CP*TP*TP*TP*AP*TP*TP*CP*CP*CP*AP*TP*GP*GP*GP*AP*AP*TP*AP*AP*AP*G)-3'), Transcription factor COE1, ZINC ION | | Authors: | Treiber, N, Treiber, T, Zocher, G, Grosschedl, R. | | Deposit date: | 2010-04-17 | | Release date: | 2010-12-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Genes Dev., 24, 2010
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5NB8
 | | Structure of vWC domain from CCN3 | | Descriptor: | GLYCEROL, IMIDAZOLE, Protein NOV homolog | | Authors: | Xu, E.-R, Hyvonen, M. | | Deposit date: | 2017-03-01 | | Release date: | 2017-06-14 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural analyses of von Willebrand factor C domains of collagen 2A and CCN3 reveal an alternative mode of binding to bone morphogenetic protein-2.
J. Biol. Chem., 292, 2017
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3MLO
 | | DNA binding domain of Early B-cell Factor 1 (Ebf1) bound to DNA (Crystal form I) | | Descriptor: | DNA (5'-D(*CP*TP*TP*TP*AP*TP*TP*CP*CP*CP*AP*TP*GP*GP*GP*AP*AP*TP*AP*AP*AP*G)-3'), Transcription factor COE1, ZINC ION | | Authors: | Treiber, N, Treiber, T, Zocher, G, Grosschedl, R. | | Deposit date: | 2010-04-17 | | Release date: | 2010-12-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Genes Dev., 24, 2010
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1DY2
 | | Murine collagen alpha1(XV), endostatin domain | | Descriptor: | COLLAGEN ALPHA1(XV) CHAIN, SULFATE ION | | Authors: | Tisi, D, Hohenester, E, Sasaki, T, Timpl, R. | | Deposit date: | 2000-01-21 | | Release date: | 2001-01-21 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Endostatin Derived from Collagens Xv and Xviii Differ in Structural and Binding Properties, Tissue Distribution and Anti-Angiogenic Activity
J.Mol.Biol., 301, 2000
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1XBR
 | | T DOMAIN FROM XENOPUS LAEVIS BOUND TO DNA | | Descriptor: | DNA (5'-D(*AP*AP*TP*TP*TP*CP*AP*CP*AP*CP*CP*TP*AP*GP*GP*TP*G P*TP*GP*AP*AP*AP* TP*T)-3'), PROTEIN (T PROTEIN) | | Authors: | Muller, C.W. | | Deposit date: | 1997-07-16 | | Release date: | 1998-01-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.
Nature, 389, 1997
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1U36
 | | Crystal structure of WLAC mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-21 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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1U3Y
 | | Crystal structure of ILAC mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-22 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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1U42
 | | Crystal structure of MLAM mutant of dimerisation domain of NF-kB p50 transcription factor | | Descriptor: | Nuclear factor NF-kappa-B p105 subunit | | Authors: | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | Deposit date: | 2004-07-23 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.699 Å) | | Cite: | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
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