5VT2

Crystal structure of growth differentiation factor

Summary for 5VT2

• Entry DOI: 10.2210/pdb5vt2/pdb
• Descriptor: Growth/differentiation factor 15, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: tgf-beta family, signaling protein
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted : Q99988
• Total number of polymer chains: 2
• Total formula weight: 24978.90

Authors

Min, X.,Wang, Z. (deposition date: 2017-05-15, release date: 2017-11-01, Last modification date: 2023-10-04)

• Primary citation: Xiong, Y.,Walker, K.,Min, X.,Hale, C.,Tran, T.,Komorowski, R.,Yang, J.,Davda, J.,Nuanmanee, N.,Kemp, D.,Wang, X.,Liu, H.,Miller, S.,Lee, K.J.,Wang, Z.,Veniant, M.M.; Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.; Sci Transl Med, 9:-, 2017; PubMed: 29046435; DOI: 10.1126/scitranslmed.aan8732

Experimental method

X-RAY DIFFRACTION (2.3 Å)