5HGU

Crystal structure of human transcription factor TEAD2 in complex with palmitate

Summary for 5HGU

• Entry DOI: 10.2210/pdb5hgu/pdb
• Related: 3L15
• Descriptor: Transcriptional enhancer factor TEF-4, PALMITIC ACID (3 entities in total)
• Functional Keywords: transcription factor, palmitoylation, hippo pathway, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 54772.16

Authors

Luo, X.,Xiao, H. (deposition date: 2016-01-08, release date: 2016-02-17, Last modification date: 2023-09-27)

• Primary citation: Chan, P.,Han, X.,Zheng, B.,DeRan, M.,Yu, J.,Jarugumilli, G.K.,Deng, H.,Pan, D.,Luo, X.,Wu, X.; Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway.; Nat.Chem.Biol., 12:282-289, 2016; PubMed: 26900866; DOI: 10.1038/nchembio.2036

Experimental method

X-RAY DIFFRACTION (2.046 Å)