PDB: 501 resultsInfo pagesStatus searchChemie searchBIRD

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4Z4H	Human Argonaute2 A481T Mutant Bound to t1-A Target RNA Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ... Authors: Schirle, N.T, MacRae, I.J. Deposit date: 2015-04-02 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.504 Å) Cite: Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife, 4, 2015
4Z4I	Human Argonaute2 A481T Mutant Bound to t1-G Target RNA Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ... Authors: Schirle, N.T, MacRae, I.J. Deposit date: 2015-04-02 Release date: 2015-09-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.801 Å) Cite: Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets. Elife, 4, 2015
6MDZ	Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2) Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ... Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-09-05 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6MFR	Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3) Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ... Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-09-12 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6MFN	Human Argonaute2-miR-27a bound to HSUR1 target RNA Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ... Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-09-11 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6N4O	Human Argonaute2-miR-122 bound to a seed and supplementary paired target Descriptor: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-11-19 Release date: 2019-05-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.899 Å) Cite: Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2. Embo J., 38, 2019
7QXS	Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) Descriptor: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... Authors: Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. Deposit date: 2022-01-27 Release date: 2022-03-02 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.91 Å) Cite: Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
7QXA	Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened) Descriptor: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... Authors: Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. Deposit date: 2022-01-26 Release date: 2022-03-02 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
7QXB	Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map) Descriptor: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... Authors: Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. Deposit date: 2022-01-26 Release date: 2022-03-02 Last modified: 2022-03-23 Method: ELECTRON MICROSCOPY (3.91 Å) Cite: Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
3OK2	Crystal structure of the ANA:RNA decamer without lattice translocation defects Descriptor: (A6C)(A6C)(A6G)(A6U)(A6A)(A6A)(A6U)(A6G)(A6C)(A6C)(PO4), GGCAUUACGG Authors: Ovaere, M, Van Meervelt, L. Deposit date: 2010-08-24 Release date: 2011-11-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.963 Å) Cite: How does hydroxyl introduction influence the double helical structure: the stabilization of an altritol nucleic acid:ribonucleic acid duplex. Nucleic Acids Res., 40, 2012
3ADL	Structure of TRBP2 and its molecule implications for miRNA processing Descriptor: RISC-loading complex subunit TARBP2, RNA (5'-R(P*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3') Authors: Yuan, Y.A, Chen, H.Y. Deposit date: 2010-01-22 Release date: 2010-05-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing Structure, 18, 2010
4J39	Crystal structure of p19 in complex with double-helical 19mer RNA p(CAG)3C(CUG)3 Descriptor: 5'-R(P*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*G)-3', RNA silencing suppressor p19, SULFATE ION Authors: Tamjar, J, Popov, A.N, Malinina, L. Deposit date: 2013-02-05 Release date: 2014-02-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Procrustean bed of RNA silencing suppression To be Published
3VYY	Structural insights into RISC assembly facilitated by dsRNA binding domains of human RNA helicase A (DHX9) Descriptor: ATP-dependent RNA helicase A, RNA (5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3') Authors: Yuan, Y.A, Fu, Q. Deposit date: 2012-10-05 Release date: 2013-02-13 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9). Nucleic Acids Res., 41, 2013
3VYX	Structural insights into RISC assembly facilitated by dsRNA binding domains of human RNA helicase (DHX9) Descriptor: ATP-dependent RNA helicase A, RNA (5'-R(P*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3') Authors: Yuan, Y.A, Fu, Q. Deposit date: 2012-10-05 Release date: 2013-02-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9). Nucleic Acids Res., 41, 2013
3LLH	Crystal structure of the first dsRBD of TAR RNA-binding protein 2 Descriptor: MALONATE ION, RISC-loading complex subunit TARBP2 Authors: Yamashita, S, Kawazoe, M, Takemoto, C, Sekine, S, Wakiyama, M, Yokoyama, S. Deposit date: 2010-01-29 Release date: 2010-12-08 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.14 Å) Cite: The structures of dsRBDs of human TRBP To be Published
7BG9	The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate Descriptor: DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ... Authors: Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. Deposit date: 2021-01-06 Release date: 2021-04-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
7ELD	Cryo-EM structure of Arabidopsis DCL1 in complex with pri-miRNA 166f Descriptor: Endoribonuclease Dicer homolog 1, pri-miRNA 166f Authors: Wei, X, Ke, H, Feng, Y. Deposit date: 2021-04-09 Release date: 2021-08-11 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Structural basis of microRNA processing by Dicer-like 1. Nat.Plants, 7, 2021
7ELE	Cryo-EM structure of Arabidopsis DCL1 in complex with pre-miRNA 166f Descriptor: Endoribonuclease Dicer homolog 1, pre-miRNA 166f Authors: Wei, X, Ke, H, Feng, Y. Deposit date: 2021-04-09 Release date: 2021-08-11 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Structural basis of microRNA processing by Dicer-like 1. Nat.Plants, 7, 2021
3GAN	Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CHLORIDE ION, Uncharacterized protein At3g22680 Authors: Burgie, E.S, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) Deposit date: 2009-02-17 Release date: 2009-03-03 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of gene product from Arabidopsis thaliana At3g22680 with bound suramin To be Published
8DFV	Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIa Descriptor: CALCIUM ION, Endoribonuclease Dcr-1, Loquacious, ... Authors: Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. Deposit date: 2022-06-22 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol.Cell, 82, 2022
8DGI	Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ia Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B Authors: Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. Deposit date: 2022-06-23 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol.Cell, 82, 2022
8DGA	Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IV Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ... Authors: Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. Deposit date: 2022-06-23 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.73 Å) Cite: Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol.Cell, 82, 2022
8DG7	Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex III Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ... Authors: Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. Deposit date: 2022-06-23 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.32 Å) Cite: Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol.Cell, 82, 2022
8DG5	Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex IIb Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B, ... Authors: Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. Deposit date: 2022-06-23 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol.Cell, 82, 2022
8DGJ	Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB - complex Ib Descriptor: Endoribonuclease Dcr-1, Loquacious, isoform B Authors: Jouravleva, K, Golovenko, D, Demo, G, Dutcher, R.C, Tanaka Hall, T.M, Zamore, P.D, Korostelev, A.A. Deposit date: 2022-06-23 Release date: 2022-11-16 Method: ELECTRON MICROSCOPY (4.02 Å) Cite: Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. Mol.Cell, 82, 2022

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