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5UI5
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BU of 5ui5 by Molmil
Crystal structure of Aquifex aeolicus sigmaN bound to promoter DNA
Descriptor: DNA (30-MER), DNA (31-MER), RNA polymerase sigma factor RpoN
Authors:Darst, S.A, Campbell, E.A, Rajashankar, K.
Deposit date:2017-01-12
Release date:2017-02-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5YIX
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BU of 5yix by Molmil
Caulobacter crescentus GcrA sigma-interacting domain (SID) in complex with domain 2 of sigma 70
Descriptor: (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, RNA polymerase sigma factor RpoD, ...
Authors:Wu, X, Zhang, Y.
Deposit date:2017-10-06
Release date:2018-03-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA.
Nucleic Acids Res., 46, 2018
4RU9
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BU of 4ru9 by Molmil
Crystal structure of human DNA polymerase eta inserting dCMPNPP opposite a MeFapy-dG adducted DNA template
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase eta, MAGNESIUM ION, ...
Authors:Patra, A, Egli, M.
Deposit date:2014-11-18
Release date:2015-08-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
3S9H
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BU of 3s9h by Molmil
RB69 DNA Polymerase Triple Mutant(L561A/S565G/Y567A) ternary complex with dUpNpp and a dideoxy-terminated primer in the presence of Ca2+
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2011-06-01
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
4RUC
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BU of 4ruc by Molmil
Crystal structure of Y-family DNA polymerase Dpo4 extending from a MeFapy-dG:dC pair
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase IV, ...
Authors:Patra, A, Banerjee, S, Stone, M.P, Egli, M.
Deposit date:2014-11-18
Release date:2015-08-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV.
J.Am.Chem.Soc., 137, 2015
4TUR
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BU of 4tur by Molmil
Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2)
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.169 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
4TUS
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BU of 4tus by Molmil
Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2) WITH MANGANESE IN THE ACTIVE SITE.
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
3SI6
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BU of 3si6 by Molmil
RB69 DNA Polymerase Triple Mutant (L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the presence of Mg2+
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2011-06-17
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
4TUQ
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BU of 4tuq by Molmil
Human DNA polymerase beta inserting dCMPNPP opposite GG template (GG0b).
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.367 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
4TUP
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BU of 4tup by Molmil
Structure of human DNA polymerase beta complexed with GG as the template (GG0b) in a 1-nucleotide gapped DNA
Descriptor: DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), DNA (5'-D(P*GP*TP*GP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
3GIM
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BU of 3gim by Molmil
Dpo4 extension ternary complex with oxoG(anti)-G(syn) pair
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DDG))-3', ...
Authors:Rechkoblit, O, Malinina, L, Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
3SJJ
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BU of 3sjj by Molmil
RB69 DNA Polymerase Triple Mutant (L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the presence of Mn2+
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2011-06-21
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
3SCX
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BU of 3scx by Molmil
RB69 DNA Polymerase Triple Mutant(L561A/S565G/Y567A) Ternary Complex with dUpNpp and a Deoxy-terminated Primer in the Presence of Ca2+
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2011-06-08
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
4XA5
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BU of 4xa5 by Molmil
Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming 8-oxo-dGTP
Descriptor: 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ACETATE ION, DNA polymerase lambda, ...
Authors:Burak, M.J, Guja, K.E, Garcia-Diaz, M.
Deposit date:2014-12-12
Release date:2016-02-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.
Nucleic Acids Res., 43, 2015
7TO2
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BU of 7to2 by Molmil
Cryo-EM structure of RIG-I bound to the internal sites of p3SLR30 (+ATP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, MAGNESIUM ION, ...
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-01-22
Release date:2022-11-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
2FMS
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BU of 2fms by Molmil
DNA Polymerase beta with a gapped DNA substrate and dUMPNPP with magnesium in the catalytic site
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ...
Authors:Batra, V.K, Beard, W.A, Shock, D.D, Krahn, J.M, Pedersen, L.C, Wilson, S.H.
Deposit date:2006-01-09
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Magnesium-induced assembly of a complete DNA polymerase catalytic complex.
Structure, 14, 2006
2FMQ
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BU of 2fmq by Molmil
Sodium in active site of DNA Polymerase Beta
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ...
Authors:Batra, V.K, Beard, W.A, Shock, D.D, Krahn, J.M, Pedersen, L.C, Wilson, S.H.
Deposit date:2006-01-09
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Magnesium-induced assembly of a complete DNA polymerase catalytic complex.
Structure, 14, 2006
3N89
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BU of 3n89 by Molmil
KH domains
Descriptor: Defective in germ line development protein 3, isoform a
Authors:Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
3GIK
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BU of 3gik by Molmil
Dpo4 extension ternary complex with the oxoG(anti)-C(anti) pair
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(DOC))-3', ...
Authors:Rechkoblit, O, Malinina, L, Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
4XIU
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BU of 4xiu by Molmil
Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant with DNA containing TTT overhang
Descriptor: DNA polymerase I, thermostable, MAGNESIUM ION, ...
Authors:Wu, E.Y.
Deposit date:2015-01-07
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase.
Biochemistry, 54, 2015
3GIJ
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BU of 3gij by Molmil
Dpo4 extension ternary complex with oxoG(syn)-A(anti) and oxoG(anti)-A(syn) pairs
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3', 5'-D(*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*(2DA))-3', ...
Authors:Rechkoblit, O, Malinina, L, Patel, D.J.
Deposit date:2009-03-05
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
Structure, 17, 2009
2FMP
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BU of 2fmp by Molmil
DNA Polymerase beta with a terminated gapped DNA substrate and ddCTP with sodium in the catalytic site
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
Authors:Batra, V.K, Beard, W.A, Shock, D.D, Krahn, J.M, Pedersen, L.C, Wilson, S.H.
Deposit date:2006-01-09
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Magnesium-induced assembly of a complete DNA polymerase catalytic complex.
Structure, 14, 2006
3SNN
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BU of 3snn by Molmil
RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite dG in the presence of Mg2+
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3', 5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2011-06-29
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into Complete Metal Ion Coordination from Ternary Complexes of B Family RB69 DNA Polymerase.
Biochemistry, 50, 2011
1N8X
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BU of 1n8x by Molmil
Solution structure of HIV-1 Stem Loop SL1
Descriptor: HIV-1 STEM LOOP SL1 MONOMERIC RNA
Authors:Lawrence, D.C, Stover, C.C, Noznitsky, J, Wu, Z, Summers, M.F.
Deposit date:2002-11-21
Release date:2003-04-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Intact Stem and Bulge of HIV-1 Psi-RNA Stem-Loop SL1
J.Mol.Biol., 326, 2003
4XUS
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BU of 4xus by Molmil
Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming dTTP
Descriptor: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*A)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Burak, M.J, Guja, K.E, Garcia-Diaz, M.
Deposit date:2015-01-26
Release date:2016-02-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.
Nucleic Acids Res., 43, 2015

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