4TUP

Structure of human DNA polymerase beta complexed with GG as the template (GG0b) in a 1-nucleotide gapped DNA

Summary for 4TUP

• Entry DOI: 10.2210/pdb4tup/pdb
• Related: 4TUQ 4TUR 4TUS
• Descriptor: DNA polymerase beta, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), ... (6 entities in total)
• Functional Keywords: dna polymerase, transferase, lyase-dna complex, lyase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 47048.95

Authors

Koag, M.C.,Lee, S. (deposition date: 2014-06-24, release date: 2014-10-01, Last modification date: 2024-03-13)

• Primary citation: Koag, M.C.,Lai, L.,Lee, S.; Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.; J.Biol.Chem., 289:31341-31348, 2014; PubMed: 25237188; DOI: 10.1074/jbc.M114.605451

Experimental method

X-RAY DIFFRACTION (1.8 Å)