4XUS
Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming dTTP
Summary for 4XUS
Entry DOI | 10.2210/pdb4xus/pdb |
Descriptor | DNA polymerase lambda, DNA (5'-D(P*GP*CP*CP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*A)-3'), ... (8 entities in total) |
Functional Keywords | dna polymerase lambda, protein-dna complex, helix-hairpin-helix, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q9UGP5 |
Total number of polymer chains | 4 |
Total formula weight | 43340.63 |
Authors | Burak, M.J.,Guja, K.E.,Garcia-Diaz, M. (deposition date: 2015-01-26, release date: 2016-02-03, Last modification date: 2024-02-28) |
Primary citation | Burak, M.J.,Guja, K.E.,Garcia-Diaz, M. Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda. Nucleic Acids Res., 43:8089-8099, 2015 Cited by PubMed: 26220180DOI: 10.1093/nar/gkv760 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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