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4XUS

Crystal structure of the pre-catalytic ternary complex of DNA polymerase lambda with a templating A and an incoming dTTP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase lambdapolymer32536448.61UniProt (Q9UGP5)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
In PDB
Homo sapiens (Human)Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa
2DDNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81synthetic construct
3PDNA (5'-D(*CP*AP*GP*TP*A)-3')polymer51504.01synthetic construct
4TDNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3')polymer113374.21synthetic construct
5ATHYMIDINE-5'-TRIPHOSPHATEnon-polymer482.21Chemie (TTP)
6AMAGNESIUM IONnon-polymer24.32Chemie (MG)
7P2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATEnon-polymer291.21Chemie (DOC)
8waterwater18.0255Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight42518.7
Non-Polymers*Number of molecules4
Total formula weight822.0
All*Total formula weight43340.6
*Water molecules are not included.

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PDB entries from 2024-09-04

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