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6TNN
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BU of 6tnn by Molmil
Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA
Descriptor: 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C.
Deposit date:2019-12-09
Release date:2020-09-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs.
Mol.Cell, 80, 2020
5DGV
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BU of 5dgv by Molmil
Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog
Descriptor: 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
Deposit date:2015-08-28
Release date:2016-12-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
4U50
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BU of 4u50 by Molmil
Crystal structure of Verrucarin bound to the yeast 80S ribosome
Descriptor: (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
6CAQ
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BU of 6caq by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
Descriptor: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:DeMirci, H.
Deposit date:2018-01-31
Release date:2018-07-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
To Be Published
5MMM
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BU of 5mmm by Molmil
Structure of the 70S chloroplast ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein 2, ...
Authors:Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N.
Deposit date:2016-12-11
Release date:2017-01-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
5GMF
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BU of 5gmf by Molmil
Crystal structure of monkey TLR7 in complex with guanosine and polyU
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Zhang, Z, Ohto, U, Shimizu, T.
Deposit date:2016-07-14
Release date:2016-11-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
Immunity, 45, 2016
5IB8
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BU of 5ib8 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNALys with U-G mismatch in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5A03
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BU of 5a03 by Molmil
Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with xylose
Descriptor: 1,4-DIETHYLENE DIOXIDE, ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Taberman, H, Rouvinen, J, Parkkinen, T.
Deposit date:2015-04-17
Release date:2015-10-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase.
Biochem.J., 472, 2015
4U8I
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BU of 4u8i by Molmil
Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A
Descriptor: 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Qureshi, I.A, Chaudhary, R, Tanner, J.J.
Deposit date:2014-08-03
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics.
Biochemistry, 53, 2014
5CZ8
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BU of 5cz8 by Molmil
Yeast 20S proteasome beta5-L(-49)S-K33A mutant in complex with Carfilzomib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-07-31
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5MKL
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BU of 5mkl by Molmil
Crystal structure of SmAP (LSm) protein from Sulfolobus acidocaldarius
Descriptor: Sm ribonucleo
Authors:Nikulin, A.D, Lekontseva, N.V, Tishchenko, S.V.
Deposit date:2016-12-05
Release date:2017-12-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.086 Å)
Cite:Crystal structures and RNA-binding properties of Lsm proteins from archaea Sulfolobus acidocaldarius and Methanococcus vannielii: Similarity and difference of the U-binding mode.
Biochimie, 175, 2020
6CB3
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BU of 6cb3 by Molmil
Crystal structure of the L.Lactis YkoY riboswitch bound to cadmium
Descriptor: BARIUM ION, CADMIUM ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Bachas, S, Ferre-D'amare, A.R.
Deposit date:2018-02-01
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.891 Å)
Cite:Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators.
Cell Chem Biol, 25, 2018
4U3U
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BU of 4u3u by Molmil
Crystal structure of Cycloheximide bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-22
Release date:2014-10-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
5D0Z
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BU of 5d0z by Molmil
Yeast 20S proteasome beta5-T1S mutant in complex with Carfilzomib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-08-03
Release date:2016-03-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5DA5
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BU of 5da5 by Molmil
Crystal structure of Rhodospirillum rubrum Rru_A0973
Descriptor: CALCIUM ION, FE (III) ION, GLYCOLIC ACID, ...
Authors:He, D, Vanden Hehier, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J.
Deposit date:2015-08-19
Release date:2016-08-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.064 Å)
Cite:Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments.
Elife, 5, 2016
5DBU
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BU of 5dbu by Molmil
Crystal structure of 2-deoxyribose-5-phosphate aldolase (1-220) from Streptococcus suis
Descriptor: Deoxyribose-phosphate aldolase
Authors:Cao, T.-P, Choi, J.M, Lee, S.H.
Deposit date:2015-08-22
Release date:2016-04-13
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.797 Å)
Cite:Structural insight for substrate tolerance to 2-deoxyribose-5-phosphate aldolase from the pathogen Streptococcus suis
J. Microbiol., 54, 2016
6CC9
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BU of 6cc9 by Molmil
NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc
Descriptor: (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ...
Authors:Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M.
Deposit date:2018-02-06
Release date:2018-09-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
4U4Z
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BU of 4u4z by Molmil
Crystal structure of Phyllanthoside bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-24
Release date:2014-10-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U6F
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BU of 4u6f by Molmil
Crystal structure of T-2 toxin bound to the yeast 80S ribosome
Descriptor: 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 18S ribosomal RNA, 25S ribosomal RNA, ...
Authors:Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
Deposit date:2014-07-28
Release date:2014-10-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U8K
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BU of 4u8k by Molmil
Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Q107A
Descriptor: 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Qureshi, I.A, Chaudhary, R, Tanner, J.J.
Deposit date:2014-08-03
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics.
Biochemistry, 53, 2014
5M73
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BU of 5m73 by Molmil
Structure of the human SRP S domain with SRP72 RNA-binding domain
Descriptor: GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ...
Authors:Becker, M.M.M, Wild, K, Sinning, I.
Deposit date:2016-10-26
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic Acids Res., 45, 2017
4ZUX
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BU of 4zux by Molmil
SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Morgan, M, Wolberger, C.
Deposit date:2015-05-17
Release date:2016-02-24
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (3.82 Å)
Cite:Structural basis for histone H2B deubiquitination by the SAGA DUB module.
Science, 351, 2016
5MP9
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BU of 5mp9 by Molmil
26S proteasome in presence of ATP (s1)
Descriptor: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ...
Authors:Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E.
Deposit date:2016-12-16
Release date:2017-03-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6TIX
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BU of 6tix by Molmil
Crystal structure of penicillin-binding protein 2 from Yersinia pestis in complex with mecillinam
Descriptor: 2-[(1R)-1-{[(E)-azepan-1-ylmethylidene]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Peptidoglycan D,D-transpeptidase MrdA
Authors:Pankov, G, Hunter, W.N, Dawson, A.
Deposit date:2019-11-22
Release date:2020-12-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of penicillin-binding protein 2 from Yersinia pestis in complex with mecillinam
To Be Published
6T9N
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BU of 6t9n by Molmil
CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Wang, Q, Pike, A.C.W, Grieben, M, Baronina, A, Nasrallah, C, Shintre, C, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2019-10-28
Release date:2019-11-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2.
Structure, 28, 2020

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