4TUR
 
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4TUQ
 | | Human DNA polymerase beta inserting dCMPNPP opposite GG template (GG0b). | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*AP*TP*GP*GP*GP*C)-3'), ... | | Authors: | Koag, M.C, Lee, S. | | Deposit date: | 2014-06-24 | | Release date: | 2014-10-01 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.367 Å) | | Cite: | Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
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6MR8
 | | D276G DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog | | Descriptor: | 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ... | | Authors: | Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. | | Deposit date: | 2018-10-11 | | Release date: | 2019-01-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.897 Å) | | Cite: | A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition.
Nucleic Acids Res., 47, 2019
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1EWR
 | | CRYSTAL STRUCTURE OF TAQ MUTS | | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS | | Authors: | Obmolova, G, Ban, C, Hsieh, P, Yang, W. | | Deposit date: | 2000-04-26 | | Release date: | 2000-10-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA.
Nature, 407, 2000
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4S05
 | | Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, DNA (26-MER), DNA-binding transcriptional regulator BasR, ... | | Authors: | Hsiao, C.D, Weng, T.H, Li, Y.C. | | Deposit date: | 2014-12-30 | | Release date: | 2015-11-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
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6NKT
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6NKY
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6NKV
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4S04
 | | Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, DNA (25-MER), DNA-binding transcriptional regulator BasR, ... | | Authors: | Hsiao, C.D, Weng, T.H, Li, Y.C. | | Deposit date: | 2014-12-30 | | Release date: | 2015-11-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
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6NKS
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6NKW
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6NL0
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6NKZ
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6NKX
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6NKR
 | | Ternary complex crystal structure of K289M variant of DNA polymerase Beta with dGTP | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | | Authors: | Batra, V.K, Wilson, S.H. | | Deposit date: | 2019-01-07 | | Release date: | 2020-01-08 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Biochemistry, 59, 2020
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6NKU
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3COA
 | | Crystal Structure of FoxO1 DBD Bound to IRE DNA | | Descriptor: | CALCIUM ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3'), ... | | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | | Deposit date: | 2008-03-27 | | Release date: | 2008-09-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
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3CO6
 | | Crystal Structure of FoxO1 DBD Bound to DBE1 DNA | | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), ... | | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | | Deposit date: | 2008-03-27 | | Release date: | 2008-09-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification.
Structure, 16, 2008
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8SY5
 | | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site | | Descriptor: | 2-oxo-2-hydroadenosine 5'-(tetrahydrogen triphosphate), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | | Deposit date: | 2023-05-24 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
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8SY6
 | | E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site | | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Shan, Z, Lyumkis, D, Oh, J, Wang, D. | | Deposit date: | 2023-05-24 | | Release date: | 2023-12-27 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | A unified Watson-Crick geometry drives transcription of six-letter expanded DNA alphabets by E. coli RNA polymerase.
Nat Commun, 14, 2023
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4RQ0
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4RQ8
 | | Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine(8-oxoG) and dATP soaked with MnCl2 for 35 s | | Descriptor: | ACETATE ION, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | | Authors: | Vyas, R, Reed, A.J, Suo, Z. | | Deposit date: | 2014-10-31 | | Release date: | 2015-04-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.
J.Am.Chem.Soc., 137, 2015
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4RQ6
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2RDJ
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4RQ1
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