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1DM9
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BU of 1dm9 by Molmil
HEAT SHOCK PROTEIN 15 KD
Descriptor: HYPOTHETICAL 15.5 KD PROTEIN IN MRCA-PCKA INTERGENIC REGION, SULFATE ION
Authors:Staker, B.L, Korber, P, Bardwell, J.C.A, Saper, M.A.
Deposit date:1999-12-14
Release date:2000-02-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Hsp15 reveals a novel RNA-binding motif.
EMBO J., 19, 2000
1DMG
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BU of 1dmg by Molmil
CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L4
Descriptor: CITRIC ACID, RIBOSOMAL PROTEIN L4
Authors:Worbs, M, Huber, R, Wahl, M.C.
Deposit date:1999-12-14
Release date:2000-12-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of ribosomal protein L4 shows RNA-binding sites for ribosome incorporation and feedback control of the S10 operon.
EMBO J., 19, 2000
7WMH
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BU of 7wmh by Molmil
A novel chemical derivative(56) of THRB agonist
Descriptor: 2-[[1-methoxy-4-oxidanyl-7-(4-phenylphenoxy)isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2
Authors:Yao, B.Q, Li, Y.
Deposit date:2022-01-14
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist.
J.Med.Chem., 65, 2022
7WMG
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A novel chemical derivative(52) of THRB agonist
Descriptor: 2-[[1-methoxy-4-oxidanyl-7-(4-phenoxyphenoxy)isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2
Authors:Yao, B.Q, Li, Y.
Deposit date:2022-01-14
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist.
J.Med.Chem., 65, 2022
7WMJ
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A novel chemical derivative(71) of THRB agonist
Descriptor: 2-[[7-[2,6-dimethyl-4-(phenylcarbonyl)phenoxy]-1-methoxy-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acid, Isoform Beta-2 of Thyroid hormone receptor beta, Nuclear receptor coactivator 2
Authors:Yao, B.Q, Li, Y.
Deposit date:2022-01-14
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor beta Agonist.
J.Med.Chem., 65, 2022
1DQP
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BU of 1dqp by Molmil
CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH IMMUCILLING
Descriptor: 1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL, GUANINE PHOSPHORIBOSYLTRANSFERASE, ISOPROPYL ALCOHOL
Authors:Shi, W, Munagala, N.R, Wang, C.C, Li, C.M, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C.
Deposit date:2000-01-04
Release date:2000-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry, 39, 2000
1DT2
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BU of 1dt2 by Molmil
CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN B
Descriptor: EXFOLIATIVE TOXIN B
Authors:Papageorgiou, A.C, Plano, L.R.W, Collins, C.M, Acharya, K.R.
Deposit date:2000-01-11
Release date:2003-01-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural similarities and differences in Staphylococcus aureus exfoliative toxins A and B as revealed by their crystal structures.
Protein Sci., 9, 2000
1DUA
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BU of 1dua by Molmil
CRYSTAL STRUCTURE OF EXFOLIATIVE TOXIN A
Descriptor: EXFOLIATIVE TOXIN A
Authors:Papageorgiou, A.C, Plano, L.R.W, Collins, C.M, Acharya, K.R.
Deposit date:2000-01-17
Release date:2003-01-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural similarities and differences in Staphylococcus aureus exfoliative toxins A and B as revealed by their crystal structures.
Protein Sci., 9, 2000
7X1Z
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BU of 7x1z by Molmil
Structure of the phosphorylation-site double mutant S431E/T432E of the KaiC circadian clock protein
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION
Authors:Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q.
Deposit date:2022-02-25
Release date:2023-04-19
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex
Nat Commun, 14, 2023
6MD2
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BU of 6md2 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Arachidonic acid
Descriptor: 2-chloro-5-nitro-N-phenylbenzamide, ARACHIDONIC ACID, Peroxisome proliferator-activated receptor gamma
Authors:Shang, J, Kojetin, D.J.
Deposit date:2018-09-03
Release date:2019-01-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
2IS3
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BU of 2is3 by Molmil
Crystal Structure of Escherichia coli RNase T
Descriptor: Ribonuclease T, SULFATE ION
Authors:Zuo, Y, Wang, Y, Malhotra, A.
Deposit date:2006-10-16
Release date:2007-04-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover.
Structure, 15, 2007
7X1Y
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BU of 7x1y by Molmil
Structure of the phosphorylation-site double mutant S431A/T432A of the KaiC circadian clock protein
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION
Authors:Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q.
Deposit date:2022-02-25
Release date:2023-04-26
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex
Nat Commun, 14, 2023
1XP3
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BU of 1xp3 by Molmil
Crystal Structure of Endonuclease IV (BA4508) from Bacillus anthracis at 2.57A Resolution.
Descriptor: SULFATE ION, ZINC ION, endonuclease IV
Authors:Fogg, M.J, Levdikov, V.M, Blagova, E.V, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE)
Deposit date:2004-10-08
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal Structure of Endonuclease IV (BA4508) from Bacillus anthracis at 2.57A Resolution.
To be Published
3OT7
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BU of 3ot7 by Molmil
Escherichia coli apo-manganese superoxide dismutase
Descriptor: Superoxide dismutase [Mn]
Authors:Whittaker, M.M, Lerch, T.F, Kirillova, O, Chapman, M.S, Whittaker, J.W.
Deposit date:2010-09-10
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Subunit dissociation and metal binding by Escherichia coli apo-manganese superoxide dismutase.
Arch.Biochem.Biophys., 505, 2011
7DQB
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BU of 7dqb by Molmil
Crystal structure of an IclR homolog complexed with 4-hydroxybenzoate from Microbacterium hydrocarbonoxydans in P212121 form
Descriptor: IclR homolog, P-HYDROXYBENZOIC ACID
Authors:Akiyama, T, Sasaki, Y, Ito, S, Yajima, S.
Deposit date:2020-12-23
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural basis of the conformational changes in Microbacterium hydrocarbonoxydans IclR transcription factor homolog due to ligand binding.
Biochim Biophys Acta Proteins Proteom, 1869, 2021
6LX7
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BU of 6lx7 by Molmil
X-ray structure of human PPARalpha ligand binding domain-stearic acid co-crystals obtained by delipidation and cross-seeding
Descriptor: GLYCEROL, Peroxisome proliferator-activated receptor alpha, STEARIC ACID
Authors:Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
Deposit date:2020-02-10
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6LXC
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BU of 6lxc by Molmil
X-ray structure of human PPARalpha ligand binding domain-saroglitazar co-crystals obtained by delipidation and cross-seeding
Descriptor: (2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoic acid, Peroxisome proliferator-activated receptor alpha
Authors:Kamata, S, Honda, A, Ishikawa, R, Akahane, M, Oyama, T, Ishii, I.
Deposit date:2020-02-10
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
6F2L
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BU of 6f2l by Molmil
Crystal structure of the complex between PPARgamma LBD and the ligand LJ570: structure obtained from crystals of the apo-form soaked for 15 days.
Descriptor: (2S)-3-(biphenyl-4-yl)-2-(biphenyl-4-yloxy)propanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Pochetti, G, Montanari, M.
Deposit date:2017-11-24
Release date:2018-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of the First PPAR alpha / gamma Dual Agonist Able To Bind to Canonical and Alternative Sites of PPAR gamma and To Inhibit Its Cdk5-Mediated Phosphorylation.
J.Med.Chem., 61, 2018
6MFR
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BU of 6mfr by Molmil
Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3)
Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-12
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
1DVE
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BU of 1dve by Molmil
CRYSTAL STRUCTURE OF RAT HEME OXYGENASE-1 IN COMPLEX WITH HEME
Descriptor: HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sugishima, M, Omata, Y, Kakuta, Y, Sakamoto, H, Noguchi, M, Fukuyama, K.
Deposit date:2000-01-20
Release date:2000-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of rat heme oxygenase-1 in complex with heme.
FEBS Lett., 471, 2000
5UZY
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BU of 5uzy by Molmil
Crystal structure of N97A mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2017-02-27
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 57, 2018
1DQN
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BU of 1dqn by Molmil
CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE
Descriptor: GUANINE PHOSPHORIBOSYLTRANSFERASE, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Shi, W, Munagala, N.R, Wang, C.C, Li, C.M, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C.
Deposit date:2000-01-04
Release date:2000-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Biochemistry, 39, 2000
6FO9
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BU of 6fo9 by Molmil
Vitamin D nuclear receptor complex 2
Descriptor: (1~{R},3~{S},5~{Z})-4-methylidene-5-[(~{E})-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]hex-2-enylidene]cyclohexane-1,3-diol, Nuclear receptor coactivator 1, Vitamin D3 receptor A
Authors:Rochel, N.
Deposit date:2018-02-06
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists.
J. Med. Chem., 61, 2018
6FOD
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BU of 6fod by Molmil
Vitamin D nuclear receptor complex 1
Descriptor: (1~{R},3~{S},5~{Z})-4-methylidene-5-[(~{E})-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]pent-2-enylidene]cyclohexane-1,3-diol, Nuclear receptor coactivator 1, Vitamin D3 receptor A
Authors:Rochel, N.
Deposit date:2018-02-07
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists.
J. Med. Chem., 61, 2018
6MFN
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BU of 6mfn by Molmil
Human Argonaute2-miR-27a bound to HSUR1 target RNA
Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ...
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-09-11
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019

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