PDB: 46006 resultsInfo pagesStatus searchChemie searchBIRD

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3K98	HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide Descriptor: (1R)-2-[(5-chloro-2,4-dihydroxyphenyl)carbonyl]-N-ethyl-2,3-dihydro-1H-isoindole-1-carboxamide, Heat shock protein HSP 90-alpha, PHOSPHATE ION Authors: Gajiwala, K.S, Davies II, J.F. Deposit date: 2009-10-15 Release date: 2010-02-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone. J.Med.Chem., 53, 2010
2Q92	E. coli methionine aminopeptidase Mn-form with inhibitor B23 Descriptor: 5-(2-NITROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... Authors: Ye, Q.-Z. Deposit date: 2007-06-12 Release date: 2008-01-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes. Bmc Struct.Biol., 7, 2007
3OG4	The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P21212 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin 28 receptor, alpha (Interferon, ... Authors: Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A. Deposit date: 2010-08-16 Release date: 2010-10-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404, 2010
6SZZ	Crystal structure of Cold Shock Protein B (CspB) containing the modified residue 4-F-Trp Descriptor: Cold shock protein CspD, GLYCEROL Authors: Zhou, T, Mayans, O. Deposit date: 2019-10-02 Release date: 2020-02-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.05 Å) Cite: What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein. Sci Rep, 10, 2020
3OG6	The crystal structure of human interferon lambda 1 complexed with its high affinity receptor in space group P212121 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Interleukin 28 receptor, ... Authors: Miknis, Z.J, Magracheva, E, Lei, W, Zdanov, A, Kotenko, S.V, Wlodawer, A. Deposit date: 2010-08-16 Release date: 2010-10-20 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.097 Å) Cite: Crystal structure of the complex of human interferon-lambda1 with its high affinity receptor interferon-lambdaR1. J.Mol.Biol., 404, 2010
3K17	Crystal structure of a Lin0012 protein from Listeria innocua Descriptor: Lin0012 protein, TRIETHYLENE GLYCOL Authors: Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-09-25 Release date: 2009-10-06 Last modified: 2021-02-10 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of a Lin0012 protein from Listeria innocua To be Published
3SY2	Crystal structure of the Salmonella E3 ubiquitin ligase SopA in complex with the human E2 UbcH7 Descriptor: E3 ubiquitin-protein ligase SopA, SULFATE ION, Ubiquitin-conjugating enzyme E2 L3 Authors: Diao, J, Lin, D.Y, Chen, J. Deposit date: 2011-07-15 Release date: 2012-01-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3.27 Å) Cite: Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions. Proc.Natl.Acad.Sci.USA, 109, 2012
2QA4	A more complete structure of the the L7/L12 stalk of the Haloarcula marismortui 50S large ribosomal subunit Descriptor: 23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L31E, 50S ribosomal protein L10e, ... Authors: Steitz, T.A, Kavran, J.M. Deposit date: 2007-06-14 Release date: 2008-04-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal subunit: Analysis of L11 movements J.Mol.Biol., 371, 2007
3T19	Crystal structure of HIV-1 reverse transcriptase (wild type) in complex with inhibitor M05 Descriptor: 1-(2,5-dichloro-3-{[5-chloro-1-(2H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1H-benzotriazol-4-yl]oxy}phenyl)methanamine, Reverse Transcriptase Authors: Yan, Y, Reid, J. Deposit date: 2011-07-21 Release date: 2011-10-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase. J.Med.Chem., 54, 2011
3K85	Crystal structure of a D-glycero-D-manno-heptose 1-phosphate kinase from Bacteriodes thetaiotaomicron Descriptor: D-glycero-D-manno-heptose 1-phosphate kinase Authors: Palani, K, Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-10-13 Release date: 2009-12-08 Last modified: 2021-02-10 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Crystal structure of a D-glycero-D-manno-heptose 1-phosphate kinase from Bacteriodes thetaiotaomicron To be Published
3K8L	Crystal structure of SusG-D498N mutant with maltoheptaose Descriptor: 1,2-ETHANEDIOL, Alpha-amylase, susG, ... Authors: Koropatkin, N.M, Smith, T.J. Deposit date: 2009-10-14 Release date: 2010-03-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: SusG: A Unique Cell-Membrane-Associated alpha-Amylase from a Prominent Human Gut Symbiont Targets Complex Starch Molecules. Structure, 18, 2010
3K97	HSP90 N-terminal domain in complex with 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol Descriptor: 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha Authors: Gajiwala, K.S. Deposit date: 2009-10-15 Release date: 2010-02-09 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone. J.Med.Chem., 53, 2010
2QOS	Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8 Descriptor: Complement component 8, gamma polypeptide, Complement component C8 alpha chain Authors: Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L. Deposit date: 2007-07-20 Release date: 2007-10-16 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding. Mol.Immunol., 45, 2008
7JZX	Cryo-EM structure of CRISPR-Cas surveillance complex with AcrIF7 Descriptor: AcrF7, CRISPR type I-F/YPEST-associated protein Csy3, CRISPR-associated endonuclease Cas6/Csy4, ... Authors: Chang, L, Li, Z, Gabel, C. Deposit date: 2020-09-02 Release date: 2020-12-30 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for inhibition of the type I-F CRISPR-Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14. Nucleic Acids Res., 49, 2021
4A37	Metallo-carboxypeptidase from Pseudomonas Aeruginosa Descriptor: METALLO-CARBOXYPEPTIDASE, ZINC ION Authors: Otero, A, Rodriguez de la Vega, M, Tanco, S.M, Lorenzo, J, Aviles, F.X, Reverter, D. Deposit date: 2011-09-30 Release date: 2012-05-09 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps. Faseb J., 26, 2012
7JZW	Cryo-EM structure of CRISPR-Cas surveillance complex with AcrIF4 Descriptor: CRISPR repeat sequence, CRISPR type I-F/YPEST-associated protein Csy1, CRISPR type I-F/YPEST-associated protein Csy2, ... Authors: Chang, L, Li, Z, Gabel, C. Deposit date: 2020-09-02 Release date: 2020-12-30 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural basis for inhibition of the type I-F CRISPR-Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14. Nucleic Acids Res., 49, 2021
3TAM	Crystal structure of HIV-1 reverse transcriptase (K103N mutant) in complex with inhibitor M06 Descriptor: 3-chloro-5-{[4-methyl-2-oxo-1-(2H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1,2-dihydropyridin-3-yl]oxy}benzonitrile, Reverse transcriptase/ribonuclease H, p51 RT Authors: Yan, Y. Deposit date: 2011-08-04 Release date: 2011-10-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Design and synthesis of pyridone inhibitors of non-nucleoside reverse transcriptase. Bioorg.Med.Chem.Lett., 21, 2011
2QG6	Crystal structure of human nicotinamide riboside kinase (NRK1) in complex with nicotinamide mononucleotide (NMN) Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide riboside kinase 1, PHOSPHATE ION Authors: Khan, J.A, Xiang, S, Tong, L. Deposit date: 2007-06-28 Release date: 2007-10-02 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of human nicotinamide riboside kinase Structure, 15, 2007
3JVC	Crystal Structure of the Lipoprotein_17 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. Northeast Structural Genomics Consortium Target UuR17a. Descriptor: Conserved hypothetical membrane lipoprotein Authors: Vorobiev, S, Neely, H, Lee, D, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) Deposit date: 2009-09-16 Release date: 2009-09-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Crystal Structure of the Lipoprotein_17 domain from Q9PRA0_UREPA protein of Ureaplasma parvum. To be Published
4ADX	The Cryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 Descriptor: 23S Ribosomal RNA EXPANSION SEGMENTS, 23S ribosomal RNA, 5S Ribosomal RNA, ... Authors: Greber, B.J, Boehringer, D, Godinic-Mikulcic, V, Crnkovic, A, Ibba, M, Weygand-Durasevic, I, Ban, N. Deposit date: 2012-01-04 Release date: 2012-02-08 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Cryo-Em Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome Evolution J.Mol.Biol., 418, 2012
2R2W	Urokinase plasminogen activator B-chain-GPPE complex Descriptor: 1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine, Plasminogen activator, urokinase, ... Authors: Zeslawska, E. Deposit date: 2007-08-28 Release date: 2007-10-23 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Geometry of GPPE binding to picrate and to the urokinase type plasminogen activator. Bioorg.Med.Chem.Lett., 17, 2007
4AGD	CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH SUNITINIB (SU11248) (N-2-diethylaminoethyl)-5-((Z)-(5- fluoro-2-oxo-1H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3- carboxamide) Descriptor: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 Authors: McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A. Deposit date: 2012-01-26 Release date: 2012-09-26 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
2QJC	Crystal structure of a putative diadenosine tetraphosphatase Descriptor: Diadenosine tetraphosphatase, putative, MANGANESE (II) ION, ... Authors: Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2007-07-06 Release date: 2007-07-24 Last modified: 2021-02-03 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
6MSF	F6 APTAMER MS2 COAT PROTEIN COMPLEX Descriptor: PROTEIN (MS2 PROTEIN CAPSID), RNA (5'-R(*CP*AP*GP*UP*CP*AP*CP*UP*GP*G)-3'), RNA (5'-R(*CP*CP*AP*CP*AP*GP*UP*CP*AP*CP*UP*GP*GP*G)-3') Authors: Convery, M.A, Rowsell, S, Stonehouse, N.J, Ellington, A.D, Hirao, I, Murray, J.B, Peabody, D.S, Phillips, S.E.V, Stockley, P.G. Deposit date: 1998-01-06 Release date: 1998-07-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution. Nat.Struct.Biol., 5, 1998
2JOI	NMR solution structure of hypothetical protein TA0095 from Thermoplasma acidophilum Descriptor: Hypothetical protein Ta0095 Authors: Jimenez, M, Leon, E, Santoro, J, Rico, M, Yee, A, Structural Genomics Consortium (SGC) Deposit date: 2007-03-13 Release date: 2007-10-02 Last modified: 2023-12-20 Method: SOLUTION NMR Cite: Solution structure of the hypothetical protein TA0095 from Thermoplasma acidophilum: A novel superfamily with a two-layer sandwich architecture Protein Sci., 16, 2007

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