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5IQ6	Crystal structure of Dengue virus serotype 3 RNA dependent RNA polymerase bound to HeE1-2Tyr, a new pyridobenzothizole inhibitor Descriptor: N-[8-(cyclohexyloxy)-1-oxo-2-phenyl-1H-pyrido[2,1-b][1,3]benzothiazole-4-carbonyl]-L-tyrosine, RNA dependent RNA polymerase, ZINC ION Authors: Tarantino, D, Mastrangelo, E, Milani, M. Deposit date: 2016-03-10 Release date: 2016-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3 Å) Cite: Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor. Antiviral Res., 134, 2016
2PGG	Crystal Structure of a Birnavirus (IBDV) RNA-dependent RNA Polymerase VP1 Descriptor: RNA-directed RNA polymerase Authors: Pan, J, Vakharia, V.N, Tao, Y.J. Deposit date: 2007-04-09 Release date: 2007-05-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The structure of a birnavirus polymerase reveals a distinct active site topology. Proc.Natl.Acad.Sci.Usa, 104, 2007
2ZTT	Crystal Structure of RNA polymerase PB1-PB2 subunits from Influenza A Virus Descriptor: Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit Authors: Sugiyama, K, Obayashi, E, Park, S.-Y. Deposit date: 2008-10-08 Release date: 2009-06-09 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase Embo J., 28, 2009
3A1G	High-Resolution Crystal Structure of RNA polymerase PB1-PB2 subunits from Influenza A Virus Descriptor: Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit Authors: Sugiyama, K, Park, S.-Y, Obayashi, E. Deposit date: 2009-04-02 Release date: 2009-06-09 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase Embo J., 28, 2009
3DDK	Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase Descriptor: RNA polymerase B3 3Dpol, SODIUM ION, SULFATE ION Authors: Campagnola, G, Weygandt, M.H, Scoggin, K.E, Peersen, O.B. Deposit date: 2008-06-05 Release date: 2008-09-23 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal Structure of Coxsackievirus B3 3Dpol Highlights Functional Importance of Residue 5 in Picornaviral Polymerases J.Virol., 82, 2008
7F0S	A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase Descriptor: RNA-directed RNA polymerase nsP4 Authors: Tan, Y.B, Luo, D. Deposit date: 2021-06-06 Release date: 2022-02-16 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold. Nucleic Acids Res., 50, 2022
1C2P	HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE Descriptor: RNA-DEPENDENT RNA POLYMERASE Authors: Lesburg, C.A, Cable, M.B, Ferrari, E, Hong, Z, Mannarino, A.F, Weber, P.C. Deposit date: 1999-07-26 Release date: 2000-04-05 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nat.Struct.Biol., 6, 1999
6BOG	Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription Descriptor: RNA polymerase-associated protein RapA, SULFATE ION Authors: Shaw, G.X, Gan, J, Zhou, Y.N, Zhang, R, Joachimiak, A, Jin, D.J, Ji, X. Deposit date: 2017-11-20 Release date: 2017-12-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.205 Å) Cite: Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription. Structure, 16, 2008
1S76	T7 RNA polymerase alpha beta methylene ATP elongation complex Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA (5'-D(P*GP*CP*CP*GP*TP*GP*CP*GP*CP*AP*TP*TP*CP*GP*CP*CP*GP*TP*GP*TP*T)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*GP*TP*TP*GP*CP*GP*CP*AP*CP*GP*GP*C)-3'), ... Authors: Yin, Y.W, Steitz, T.A. Deposit date: 2004-01-29 Release date: 2004-03-23 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.88 Å) Cite: The structural mechanism of translocation and helicase activity in T7 RNA polymerase. Cell(Cambridge,Mass.), 116, 2004
1COO	THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT Descriptor: RNA POLYMERASE ALPHA SUBUNIT Authors: Jeon, Y.H, Negishi, T, Shirakawa, M, Yamazaki, T, Fujita, N, Ishihama, A, Kyogoku, Y. Deposit date: 1995-10-09 Release date: 1996-03-08 Last modified: 2024-04-10 Method: SOLUTION NMR Cite: Solution structure of the activator contact domain of the RNA polymerase alpha subunit. Science, 270, 1995
1DOQ	THE C-TERMINAL DOMAIN OF THE RNA POLYMERASE ALPHA SUBUNIT FROM THERMUS THERMOPHILUS Descriptor: RNA POLYMERASE ALPHA SUBUNIT Authors: Wada, T, Yamazaki, T, Kyogoku, Y. Deposit date: 1999-12-21 Release date: 2000-01-05 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The structure and the characteristic DNA binding property of the C-terminal domain of the RNA polymerase alpha subunit from Thermus thermophilus. J.Biol.Chem., 275, 2000
4A8F	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*DAP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8S	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8Q	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*DTP*TP*CP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8M	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*AP*AP*TP*CP)-3', ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8O	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8K	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*AP*AP*TP*CP)-3', 5'-D(*TP*CP)-3', GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
2JL9	Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase Descriptor: RNA-DIRECTED RNA POLYMERASE Authors: Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2008-09-05 Release date: 2008-11-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
4PN1	Structure of S. pombe Pct1 RNA triphosphatase in complex with the Spt5 CTD Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Synthetic peptide, ... Authors: Lima, C.D, Doamekpor, S.K. Deposit date: 2014-05-22 Release date: 2014-11-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.803 Å) Cite: Fission yeast RNA triphosphatase reads an Spt5 CTD code. Rna, 21, 2015
4A8Y	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
4A8W	Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation Descriptor: 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. Deposit date: 2011-11-21 Release date: 2012-07-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
1S48	Crystal structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from BVDV Descriptor: RNA-dependent RNA polymerase Authors: Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G. Deposit date: 2004-01-15 Release date: 2004-04-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (3 Å) Cite: The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc.Natl.Acad.Sci.Usa, 101, 2004
1S4F	Crystal Structure of RNA-dependent RNA polymerase construct 2 from bovine viral diarrhea virus (BVDV) Descriptor: RNA-dependent RNA polymerase Authors: Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G. Deposit date: 2004-01-16 Release date: 2004-04-06 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3 Å) Cite: The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc.Natl.Acad.Sci.Usa, 101, 2004
2HCS	Crystal structure of RNA dependant RNA polymerase domain of West Nile virus Descriptor: RNA-directed RNA polymerase (NS5), ZINC ION Authors: Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP) Deposit date: 2006-06-18 Release date: 2007-02-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 J.Biol.Chem., 282, 2007
2ZNL	Crystal structure of PA-PB1 complex form influenza virus RNA polymerase Descriptor: Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit Authors: Obayashi, E, Yoshida, H, Kawai, F, Shibayama, N, Kawaguchi, A, Nagata, K, Tame, J.R.H, Park, S.-Y. Deposit date: 2008-04-28 Release date: 2008-09-02 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structural basis for an essential subunit interaction in influenza virus RNA polymerase Nature, 454, 2008

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