1S48
Crystal structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from BVDV
Summary for 1S48
Entry DOI | 10.2210/pdb1s48/pdb |
Related | 1S49 1S4F |
Descriptor | RNA-dependent RNA polymerase (1 entity in total) |
Functional Keywords | polymerase, primer independent initiation, de novo initiation, rna virus, bvdv, bovine viral diarrhea virus, replication, rna binding protein |
Biological source | Bovine viral diarrhea virus 1 |
Cellular location | E(rns) glycoprotein: Host membrane; Peripheral membrane protein. Envelope glycoprotein E2: Host cell surface. Cysteine protease NS2: Host membrane; Multi- pass membrane protein (Potential): P19711 |
Total number of polymer chains | 1 |
Total formula weight | 70490.74 |
Authors | Choi, K.H.,Groarke, J.M.,Young, D.C.,Kuhn, R.J.,Smith, J.L.,Pevear, D.C.,Rossmann, M.G. (deposition date: 2004-01-15, release date: 2004-04-06, Last modification date: 2011-07-13) |
Primary citation | Choi, K.H.,Groarke, J.M.,Young, D.C.,Kuhn, R.J.,Smith, J.L.,Pevear, D.C.,Rossmann, M.G. The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc.Natl.Acad.Sci.Usa, 101:4425-4430, 2004 Cited by PubMed: 15070734DOI: 10.1073/pnas.0400660101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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