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3DI2
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BU of 3di2 by Molmil
Crystal structure of the complex of human interleukin-7 with unglycosylated human interleukin-7 receptor alpha ectodomain
Descriptor: Interleukin-7, Interleukin-7 receptor subunit alpha, PENTAETHYLENE GLYCOL
Authors:McElroy, C.A, Dohm, J.A, Walsh, S.T.R.
Deposit date:2008-06-19
Release date:2009-01-27
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Biophysical Studies of the Human IL-7/IL-7Ralpha Complex.
Structure, 17, 2009
1EBP
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BU of 1ebp by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN AGONIST PEPTIDE [EMP1]
Descriptor: EPO MIMETICS PEPTIDE 1, EPO RECEPTOR
Authors:Livnah, O, Stura, E.A, Wilson, I.A.
Deposit date:1996-05-07
Release date:1997-07-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.
Science, 273, 1996
1ERN
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BU of 1ern by Molmil
NATIVE STRUCTURE OF THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP]
Descriptor: PROTEIN (ERYTHROPOIETIN RECEPTOR)
Authors:Livnah, O, Stura, E.A, Wilson, I.A.
Deposit date:1999-01-11
Release date:2000-01-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation.
Science, 283, 1999
4BK5
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BU of 4bk5 by Molmil
crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample)
Descriptor: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
Authors:Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
Deposit date:2013-04-22
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKF
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BU of 4bkf by Molmil
crystal structure of the human EphA4 ectodomain in complex with human ephrinB3
Descriptor: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3
Authors:Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
Deposit date:2013-04-24
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.65 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BQ7
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BU of 4bq7 by Molmil
Crystal structure of the RGMB-Neo1 complex form 2
Descriptor: NEOGENIN, RGM DOMAIN FAMILY MEMBER B
Authors:Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
Deposit date:2013-05-30
Release date:2013-06-12
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (6.601 Å)
Cite:Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
4BQ8
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BU of 4bq8 by Molmil
Crystal structure of the RGMB-NEO1 complex form 3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B
Authors:Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
Deposit date:2013-05-30
Release date:2013-06-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
4Y5Y
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BU of 4y5y by Molmil
Diabody 330 complex with EpoR
Descriptor: Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4BKA
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BU of 4bka by Molmil
crystal structure of the human EphA4 ectodomain in complex with human ephrin A5
Descriptor: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
Authors:Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
Deposit date:2013-04-23
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (5.3 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4Y5X
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BU of 4y5x by Molmil
Diabody 305 complex with EpoR
Descriptor: CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4BK4
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BU of 4bk4 by Molmil
crystal structure of the human EphA4 ectodomain
Descriptor: EPHRIN TYPE-A RECEPTOR 4
Authors:Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
Deposit date:2013-04-22
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4YH7
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BU of 4yh7 by Molmil
Crystal structure of PTPdelta ectodomain in complex with IL1RAPL1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-27
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4Y61
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BU of 4y61 by Molmil
Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 2
Authors:Yamgata, A, Sato, Y, Goto-Ito, S, Uemura, T, Maeda, A, Shiroshima, T, Yoshida, T, Fukai, S.
Deposit date:2015-02-12
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.358 Å)
Cite:Structure of Slitrk2-PTP delta complex reveals mechanisms for splicing-dependent trans-synaptic adhesion.
Sci Rep, 5, 2015
4BQ6
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BU of 4bq6 by Molmil
Crystal structure of the RGMB-NEO1 complex form 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B
Authors:Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
Deposit date:2013-05-30
Release date:2013-06-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
4YFG
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BU of 4yfg by Molmil
Crystal structure of PTP delta meA3/meB minus variant Ig1-Fn1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.491 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4Y5V
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BU of 4y5v by Molmil
Diabody 305 complex with EpoR
Descriptor: DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4YFD
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BU of 4yfd by Molmil
Crystal structure PTP delta Ig1-Fn2 in complex with IL-1RAcP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Receptor-type tyrosine-protein phosphatase delta
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
1EER
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BU of 1eer by Molmil
CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS
Descriptor: ERYTHROPOIETIN, ERYTHROPOIETIN RECEPTOR
Authors:Syed, R.S, Li, C.
Deposit date:1998-07-24
Release date:1999-10-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Efficiency of signalling through cytokine receptors depends critically on receptor orientation.
Nature, 395, 1998
1EBA
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BU of 1eba by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN INACTIVE PEPTIDE [EMP33] CONTAINS 3,5-DIBROMOTYROSINE IN POSITION 4 (DENOTED DBY)
Descriptor: PROTEIN (EPO MIMETICS PEPTIDE 33), PROTEIN (ERYTHROPOIETIN RECEPTOR)
Authors:Livnah, O, Stura, E.A, Wilson, I.A.
Deposit date:1998-10-02
Release date:1998-11-11
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Nat.Struct.Biol., 5, 1998
1F6F
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BU of 1f6f by Molmil
CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR
Descriptor: PLACENTAL LACTOGEN, PROLACTIN RECEPTOR
Authors:Elkins, P.A, Christinger, H.W, Sandowski, Y, Sakal, E, Gertler, A, De Vos, A.M, Kossiakoff, A.A.
Deposit date:2000-06-21
Release date:2000-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Nat.Struct.Biol., 7, 2000
1HWH
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BU of 1hwh by Molmil
1:1 COMPLEX OF HUMAN GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN
Descriptor: GROWTH HORMONE, GROWTH HORMONE BINDING PROTEIN
Authors:Sundstrom, S.M, Lundqvist, T.
Deposit date:1996-11-13
Release date:1997-11-19
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution.
J.Biol.Chem., 271, 1996
1TDQ
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BU of 1tdq by Molmil
Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins
Descriptor: Aggrecan core protein, CALCIUM ION, Tenascin-R
Authors:Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T.
Deposit date:2004-05-24
Release date:2004-08-31
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins
Structure, 12, 2004
2JIX
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BU of 2jix by Molmil
Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor
Descriptor: ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR
Authors:Liu, Z, Stoll, V.S, DeVries, P, Jakob, C.G, Xie, N, Simmer, R.L, Lacy, S.E, Egan, D.A, Harlan, J.E, Lesniewski, R.R, Reilly, E.B.
Deposit date:2007-07-02
Release date:2007-07-10
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site.
Blood, 110, 2007
2JLL
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BU of 2jll by Molmil
Crystal structure of NCAM2 IgIV-FN3II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Kulahin, N, Rasmussen, K, Kristensen, O, Kastrup, J, Berezin, V, Bock, E, Walmod, P, Gajhede, M.
Deposit date:2008-09-10
Release date:2009-11-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Model and Trans-Interaction of the Entire Ectodomain of the Olfactory Cell Adhesion Molecule.
Structure, 19, 2011
2UVE
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BU of 2uve by Molmil
Structure of Yersinia enterocolitica Family 28 Exopolygalacturonase
Descriptor: ACETATE ION, EXOPOLYGALACTURONASE, NICKEL (II) ION, ...
Authors:Abbott, D.W, Boraston, A.B.
Deposit date:2007-03-09
Release date:2007-05-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The Structural Basis for Exopolygalacturonase Activity in a Family 28 Glycoside Hydrolase.
J.Mol.Biol., 368, 2007

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