2FCZ
| HIV-1 DIS kissing-loop in complex with ribostamycin | Descriptor: | HIV-1 DIS RNA, POTASSIUM ION, RIBOSTAMYCIN | Authors: | Ennifar, E, Paillart, J.C, Marquet, R, Dumas, P. | Deposit date: | 2005-12-13 | Release date: | 2006-05-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell. Nucleic Acids Res., 34, 2006
|
|
3CF2
| Structure of P97/vcp in complex with ADP/AMP-PNP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | Deposit date: | 2008-03-01 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change. Structure, 16, 2008
|
|
2O4F
| Structure of a parallel-stranded guanine tetraplex crystallised with monovalent ions | Descriptor: | 5'-D(*TP*GP*GP*GP*GP*T)-3', LITHIUM ION, SODIUM ION | Authors: | Creze, C, Rinaldi, B, Haser, R, Bouvet, P, Gouet, P. | Deposit date: | 2006-12-04 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a d(TGGGGT) quadruplex crystallized in the presence of Li+ ions. Acta Crystallogr.,Sect.D, 63, 2007
|
|
2YFE
| |
2FZZ
| Factor Xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one | Descriptor: | 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2'-{[(3R)-3-HYDROXYPYRROLIDIN-1-YL]METHYL}BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-1,4,5,6-TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE, Coagulation factor X | Authors: | Alexander, R.S. | Deposit date: | 2006-02-10 | Release date: | 2006-06-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. Bioorg.Med.Chem.Lett., 16, 2006
|
|
2G5K
| Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with Apramycin | Descriptor: | 5'-R(*UP*UP*GP*CP*GP*UP*CP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*AP*GP*UP*CP*GP*C)-3', APRAMYCIN, COBALT HEXAMMINE(III), ... | Authors: | Kondo, J, Francois, B, Urzhumtsev, A, Westhof, E. | Deposit date: | 2006-02-23 | Release date: | 2006-06-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site Complexed with Apramycin Angew.Chem.Int.Ed.Engl., 45, 2006
|
|
2GIS
| |
2YJD
| Stapled peptide bound to Estrogen Receptor Beta | Descriptor: | 4-(2-PROPAN-2-YLOXYBENZIMIDAZOL-1-YL)PHENOL, ESTROGEN RECEPTOR BETA, STAPLED PEPTIDE | Authors: | Phillips, C, Roberts, L.R, Schade, M, Bent, A, Davies, N.L, Moore, R, Pannifer, A.D, Brown, D.G, Pickford, A.R, Irving, S.L. | Deposit date: | 2011-05-19 | Release date: | 2011-08-03 | Last modified: | 2017-01-25 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Design and Structure of Stapled Peptides Binding to Estrogen Receptors. J.Am.Chem.Soc., 133, 2011
|
|
2F4S
| A-site RNA in complex with neamine | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 5'-R(P*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | Deposit date: | 2005-11-24 | Release date: | 2006-05-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site Chem.Biol., 13, 2006
|
|
3CF3
| Structure of P97/vcp in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | Deposit date: | 2008-03-01 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change. Structure, 16, 2008
|
|
2GU5
| |
2CS8
| |
2CSX
| Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met) | Descriptor: | Methionyl-tRNA synthetase, RNA (75-MER) | Authors: | Nakanishi, K, Ogiso, Y, Nakama, T, Fukai, S, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-23 | Release date: | 2005-09-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nat.Struct.Mol.Biol., 12, 2005
|
|
2CT8
| Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met) and methionyl-adenylate anologue | Descriptor: | 5'-O-[(L-METHIONYL)-SULPHAMOYL]ADENOSINE, Methionyl-tRNA synthetase, RNA (74-MER) | Authors: | Nakanishi, K, Ogiso, Y, Nakama, T, Fukai, S, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-23 | Release date: | 2005-09-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nat.Struct.Mol.Biol., 12, 2005
|
|
2D04
| Crystal structure of neoculin, a sweet protein with taste-modifying activity. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Curculin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Shimizu-Ibuka, A, Morita, Y, Terada, T, Asakura, T, Nakajima, K, Iwata, S, Misaka, T, Sorimachi, H, Arai, S, Abe, K. | Deposit date: | 2005-07-25 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Crystal structure of neoculin: insights into its sweetness and taste-modifying activity J.Mol.Biol., 359, 2006
|
|
3CF1
| Structure of P97/vcp in complex with ADP/ADP.alfx | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Transitional endoplasmic reticulum ATPase | Authors: | Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I. | Deposit date: | 2008-03-01 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change. Structure, 16, 2008
|
|
1Q88
| |
2GPW
| Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli. | Descriptor: | Biotin carboxylase | Authors: | Shen, Y, Chou, C.Y, Chang, G.G, Tong, L. | Deposit date: | 2006-04-18 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Is dimerization required for the catalytic activity of bacterial biotin carboxylase? Mol.Cell, 22, 2006
|
|
2G1J
| Crystal structure of Mycobacterium tuberculosis Shikimate Kinase at 2.0 angstrom resolution | Descriptor: | SULFATE ION, Shikimate kinase | Authors: | Gan, J, Gu, Y, Li, Y, Yan, H, Ji, X. | Deposit date: | 2006-02-14 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue. Biochemistry, 45, 2006
|
|
2G9C
| Modified pyrimidines Specifically bind the purine riboswitch | Descriptor: | ACETATE ION, COBALT HEXAMMINE(III), PYRIMIDINE-2,4,6-TRIAMINE, ... | Authors: | Gilbert, S.D, Mediatore, S.J, Batey, R.T. | Deposit date: | 2006-03-06 | Release date: | 2006-11-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Modified pyrimidines specifically bind the purine riboswitch. J.Am.Chem.Soc., 128, 2006
|
|
2GSL
| X-Ray Crystal Structure of Protein FN1578 from Fusobacterium nucleatum. Northeast Structural Genomics Consortium Target NR1. | Descriptor: | Hypothetical protein, MAGNESIUM ION | Authors: | Forouhar, F, Su, M, Jayaraman, S, Conover, K, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-04-26 | Release date: | 2006-05-09 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of the Hypothetical Protein (FN1578) from Fusobacterium nucleatum, NESG Target NR1 To be Published
|
|
2GU7
| E. coli methionine aminopeptidase unliganded, 1:0.5 | Descriptor: | MANGANESE (II) ION, Methionine aminopeptidase, SODIUM ION | Authors: | Ye, Q.Z. | Deposit date: | 2006-04-28 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of catalysis by monometalated methionine aminopeptidase. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2LK2
| Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, Northeast Structural Genomics Consortium Target HR4411B | Descriptor: | Homeobox protein TGIF1 | Authors: | Yang, Y, Ramelot, T.A, Cort, J.R, Shastry, R, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-09-30 | Release date: | 2011-10-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of homeobox domain (171-248) of human homeobox protein TGIF1, Northeast Structural Genomics Consortium Target HR4411B. To be Published
|
|
2DRA
| Complex structure of CCA-adding enzyme with tRNAminiDCC and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CCA-adding enzyme, MAGNESIUM ION, ... | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-06-08 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
|
|
2DR5
| Complex structure of CCA adding enzyme with mini-helix lacking CCA | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (32-MER) | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-06-08 | Release date: | 2006-10-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
|
|