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6N6T
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OXA-23 mutant F110A/M221A low pH form
Descriptor: Beta-lactamase oxa23, CITRATE ANION
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6Y
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OXA-23 mutant F110A/M221A neutral pH form meropenem complex
Descriptor: Beta-lactamase oxa23, meropenem, bound form
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6NLW
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The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1
Descriptor: Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Tan, K, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-01-09
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1
To Be Published
6NHU
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BU of 6nhu by Molmil
Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum
Descriptor: 1,2-ETHANEDIOL, Beta-lactamase, GLYCEROL, ...
Authors:Kim, Y, Welk, L, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-12-23
Release date:2019-01-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum
To Be Published
6NHS
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BU of 6nhs by Molmil
Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc
Descriptor: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
Authors:Kim, Y, Tesar, C, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-12-23
Release date:2019-01-16
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc
To Be Published
6NZ8
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Structure of carbamylated apo OXA-231 carbapenemase
Descriptor: Beta-lactamase OXA-231, CHLORIDE ION, SODIUM ION
Authors:Favaro, D.C, Llontop, E.E, Vasconcelos, F.N, Antunes, V.U, Farah, S.C, Lincopan, N.
Deposit date:2019-02-13
Release date:2020-02-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Importance of the beta 5-beta 6 Loop for the Structure, Catalytic Efficiency, and Stability of Carbapenem-Hydrolyzing Class D beta-Lactamase Subfamily OXA-143.
Biochemistry, 58, 2019
6O9S
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BU of 6o9s by Molmil
Crystal structure of Staphylococcus aureus MecR1 antibiotic-sensor domain in complex with avibactam
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Methicillin resistance mecR1 protein, SULFATE ION
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2019-03-14
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus .
J.Biol.Chem., 295, 2020
6O9W
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BU of 6o9w by Molmil
Crystal structure of Staphylococcus aureus BlaR1 antibiotic-sensor domain in complex with avibactam
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Regulatory protein BlaR1
Authors:Alexander, J.A.N, Strynadka, N.C.J.
Deposit date:2019-03-15
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus .
J.Biol.Chem., 295, 2020
6N6U
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BU of 6n6u by Molmil
OXA-23 mutant F110A/M221A low pH form imipenem complex
Descriptor: Beta-lactamase, Imipenem
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6N6X
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BU of 6n6x by Molmil
OXA-23 mutant F110A/M221A neutral pH form imipenem complex
Descriptor: Beta-lactamase oxa23, Imipenem, SULFATE ION
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2018-11-27
Release date:2018-12-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases.
Antimicrob. Agents Chemother., 63, 2019
6P56
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Crystal structure of the transpeptidase domain of a T498A mutant of PBP2 from Neisseria gonorrhoeae
Descriptor: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
Authors:Singh, A, Davies, C.
Deposit date:2019-05-29
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P52
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BU of 6p52 by Molmil
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae with a bound phosphate at the active site
Descriptor: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
Authors:Singh, A, Davies, C.
Deposit date:2019-05-29
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6P96
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BU of 6p96 by Molmil
OXA-48 carbapanemase, apo form
Descriptor: Beta-lactamase, CADMIUM ION, CALCIUM ION, ...
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2019-06-10
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase.
Antimicrob.Agents Chemother., 63, 2019
6P9C
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BU of 6p9c by Molmil
OXA-48 carbapanemase, doripenem complex
Descriptor: (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, CADMIUM ION, ...
Authors:Smith, C.A, Vakulenko, S.B.
Deposit date:2019-06-10
Release date:2019-08-07
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase.
Antimicrob.Agents Chemother., 63, 2019
6P53
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BU of 6p53 by Molmil
Crystal structure of the transpeptidase domain of PBP2 from Neisseria gonorrhoeae in apo form
Descriptor: PHOSPHATE ION, peptidoglycan D,D-transpeptidase PenA
Authors:Singh, A, Davies, C.
Deposit date:2019-05-29
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2.
J.Biol.Chem., 294, 2019
6HB8
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BU of 6hb8 by Molmil
Crystal structure of OXA-517 beta-lactamase
Descriptor: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, Beta-lactamase, ...
Authors:Raczynska, J.E, Dabos, L, Zavala, A, Retailleau, P, Iorga, B, Jaskolski, M, Naas, T.
Deposit date:2018-08-09
Release date:2019-08-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Genetic, biochemical and structural characterization of OXA-517, an OXA-48-like extended-spectrum cephalosporins and carbapenems-hydrolyzing beta-lactamase
To Be Published
6HZI
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BU of 6hzi by Molmil
Apo structure of TP domain from Burkholderia pseudomallei penicillin-binding protein 3
Descriptor: Peptidoglycan D,D-transpeptidase FtsI
Authors:Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
Deposit date:2018-10-23
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Apo structure of TP domain from Burkholderia pseudomallei penicillin-binding protein 3
To Be Published
6HZO
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BU of 6hzo by Molmil
Apo structure of TP domain from Haemophilus influenzae Penicillin-Binding Protein 3
Descriptor: FtsI
Authors:Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
Deposit date:2018-10-23
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6HZQ
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BU of 6hzq by Molmil
Apo structure of TP domain from Escherichia coli Penicillin-Binding Protein 3
Descriptor: Peptidoglycan D,D-transpeptidase FtsI
Authors:Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
Deposit date:2018-10-23
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6GOA
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BU of 6goa by Molmil
Structural basis for OXA-48 dimerization - R189A mutant
Descriptor: Beta-lactamase, CHLORIDE ION
Authors:Lund, B.A, Thomassen, A.M, Leiros, H.K.S.
Deposit date:2018-06-01
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
6I1I
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BU of 6i1i by Molmil
Crystal structure of TP domain from Escherichia coli penicillin-binding protein 3 in complex with penicillin
Descriptor: Peptidoglycan D,D-transpeptidase FtsI,Peptidoglycan D,D-transpeptidase FtsI, Piperacillin (Open Form)
Authors:Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
Deposit date:2018-10-28
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6HOO
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BU of 6hoo by Molmil
Crystal Structure of Rationally Designed OXA-48loop18 beta-lactamase
Descriptor: Beta-lactamase,OXA-48loop18,Beta-lactamase, FLUORIDE ION, GLYCEROL, ...
Authors:Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B.
Deposit date:2018-09-17
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Substrate Specificity of OXA-48 after beta 5-beta 6 Loop Replacement.
Acs Infect Dis., 6, 2020
6HUH
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BU of 6huh by Molmil
CRYSTAL STRUCTURE OF OXA-427 class D BETA-LACTAMASE
Descriptor: Beta-lactamase, SULFATE ION
Authors:Zavala, A, Retailleau, P, Bogaerts, P, Glupczynski, Y, Naas, T, Iorga, B.
Deposit date:2018-10-08
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:CRYSTAL STRUCTURE OF CMY-OXA-427-HisTag BETA-LACTAMASE
To be published
6HZJ
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BU of 6hzj by Molmil
Apo structure of TP domain from clinical penicillin-resistant mutant Neisseria gonorrhoea strain 6140 Penicillin-Binding Protein 2 (PBP2)
Descriptor: Probable peptidoglycan D,D-transpeptidase PenA
Authors:Bellini, D, Koekemoer, L, Newman, H, Dowson, C.G.
Deposit date:2018-10-23
Release date:2019-11-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
6I5D
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BU of 6i5d by Molmil
Crystal structure of an OXA-48 beta-lactamase synthetic mutant
Descriptor: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
Authors:Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B.
Deposit date:2018-11-13
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Substrate specificity of an OXA-48 beta-lactamase synthetic mutant
To be published

221716

건을2024-06-26부터공개중

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