6HOO
Crystal Structure of Rationally Designed OXA-48loop18 beta-lactamase
Summary for 6HOO
| Entry DOI | 10.2210/pdb6hoo/pdb |
| Descriptor | Beta-lactamase,OXA-48loop18,Beta-lactamase, SULFATE ION, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | class d beta-lactamase oxa-48loop18, antibiotic, hydrolase |
| Biological source | Klebsiella pneumoniae More |
| Total number of polymer chains | 2 |
| Total formula weight | 59415.66 |
| Authors | Zavala, A.,Retailleau, P.,Dabos, L.,Naas, T.,Iorga, B. (deposition date: 2018-09-17, release date: 2019-10-09, Last modification date: 2024-01-24) |
| Primary citation | Dabos, L.,Zavala, A.,Bonnin, R.A.,Beckstein, O.,Retailleau, P.,Iorga, B.I.,Naas, T. Substrate Specificity of OXA-48 after beta 5-beta 6 Loop Replacement. Acs Infect Dis., 6:1032-1043, 2020 Cited by PubMed: 32156115DOI: 10.1021/acsinfecdis.9b00452 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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