6P56

Crystal structure of the transpeptidase domain of a T498A mutant of PBP2 from Neisseria gonorrhoeae

Summary for 6P56

Entry DOI	10.2210/pdb6p56/pdb
Descriptor	peptidoglycan D,D-transpeptidase PenA, PHOSPHATE ION (3 entities in total)
Functional Keywords	penicillin-binding protein, transpeptidase domain, neisseria gonorrhoeae, antibiotic resistance, hydrolase
Biological source	Neisseria gonorrhoeae
Total number of polymer chains	2
Total formula weight	70687.45
Authors	Singh, A.,Davies, C. (deposition date: 2019-05-29, release date: 2019-08-07, Last modification date: 2024-03-13)
Primary citation	Singh, A.,Tomberg, J.,Nicholas, R.A.,Davies, C. Recognition of the beta-lactam carboxylate triggers acylation ofNeisseria gonorrhoeaepenicillin-binding protein 2. J.Biol.Chem., 294:14020-14032, 2019 Cited by PubMed: 31362987 DOI: 10.1074/jbc.RA119.009942 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.92 Å)

Structure validation