6O9S
Crystal structure of Staphylococcus aureus MecR1 antibiotic-sensor domain in complex with avibactam
Summary for 6O9S
| Entry DOI | 10.2210/pdb6o9s/pdb |
| Descriptor | Methicillin resistance mecR1 protein, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | beta-lactam antibiotic sensor domain, antibiotic complex, signaling protein |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 1 |
| Total formula weight | 30591.77 |
| Authors | Alexander, J.A.N.,Strynadka, N.C.J. (deposition date: 2019-03-14, release date: 2020-06-10, Last modification date: 2023-10-11) |
| Primary citation | Alexander, J.A.N.,Radaeva, M.,King, D.T.,Chambers, H.F.,Cherkasov, A.,Chatterjee, S.S.,Strynadka, N.C.J. Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus . J.Biol.Chem., 295:10870-10884, 2020 Cited by PubMed: 32518158DOI: 10.1074/jbc.RA120.013029 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
Download full validation report
