6O9W
Crystal structure of Staphylococcus aureus BlaR1 antibiotic-sensor domain in complex with avibactam
Summary for 6O9W
| Entry DOI | 10.2210/pdb6o9w/pdb |
| Descriptor | Regulatory protein BlaR1, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total) |
| Functional Keywords | beta-lactam antibiotic sensor domain, antibiotic complex, penicillin binding protein, signaling protein |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 2 |
| Total formula weight | 61365.05 |
| Authors | Alexander, J.A.N.,Strynadka, N.C.J. (deposition date: 2019-03-15, release date: 2020-06-10, Last modification date: 2023-10-11) |
| Primary citation | Alexander, J.A.N.,Radaeva, M.,King, D.T.,Chambers, H.F.,Cherkasov, A.,Chatterjee, S.S.,Strynadka, N.C.J. Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus . J.Biol.Chem., 295:10870-10884, 2020 Cited by PubMed: 32518158DOI: 10.1074/jbc.RA120.013029 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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