6O9W
Crystal structure of Staphylococcus aureus BlaR1 antibiotic-sensor domain in complex with avibactam
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue NXL A 601 |
| Chain | Residue |
| A | ASN388 |
| A | GLY528 |
| A | THR529 |
| A | GLY530 |
| A | ILE531 |
| A | HOH710 |
| B | ILE531 |
| B | ASN533 |
| B | GLY534 |
| B | NXL601 |
| A | SER389 |
| A | LYS392 |
| A | SER437 |
| A | ASN439 |
| A | MET476 |
| A | GLU477 |
| A | LYS526 |
| A | THR527 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide NXL B 601 and SER B 389 |
| Chain | Residue |
| A | ILE531 |
| A | GLY534 |
| A | NXL601 |
| A | HOH710 |
| B | PRO387 |
| B | ASN388 |
| B | THR390 |
| B | TYR391 |
| B | LYS392 |
| B | SER437 |
| B | ASN439 |
| B | MET476 |
| B | GLU477 |
| B | LYS526 |
| B | THR527 |
| B | GLY528 |
| B | THR529 |
| B | GLY530 |
| B | ILE531 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide NXL B 601 and SER B 389 |
| Chain | Residue |
| A | ILE531 |
| A | GLY534 |
| A | NXL601 |
| A | HOH710 |
| B | PRO387 |
| B | ASN388 |
| B | THR390 |
| B | TYR391 |
| B | LYS392 |
| B | SER437 |
| B | ASN439 |
| B | MET476 |
| B | GLU477 |
| B | LYS526 |
| B | THR527 |
| B | GLY528 |
| B | THR529 |
| B | GLY530 |
| B | ILE531 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"15506754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21775440","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PubMed","id":"12591921","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
