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1K4B
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STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES
Descriptor: 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3'
Authors:Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
Deposit date:2001-10-07
Release date:2001-12-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
1K4A
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BU of 1k4a by Molmil
STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES
Descriptor: 5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3'
Authors:Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J.
Deposit date:2001-10-07
Release date:2001-12-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III.
EMBO J., 20, 2001
3PIF
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BU of 3pif by Molmil
Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant in Complex with Manganese
Descriptor: 5'->3' EXORIBONUCLEASE (xrn1), MANGANESE (II) ION
Authors:Chang, J.H, Xiang, S, Tong, L.
Deposit date:2010-11-06
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
3PIE
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BU of 3pie by Molmil
Crystal structure of the 5'->3' exoribonuclease Xrn1, E178Q mutant
Descriptor: 5'->3' EXORIBONUCLEASE (Xrn1)
Authors:Chang, J.H, Xiang, S, Tong, L.
Deposit date:2010-11-06
Release date:2011-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and biochemical studies of the 5' -> 3' exoribonuclease Xrn1.
Nat.Struct.Mol.Biol., 18, 2011
2NUB
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BU of 2nub by Molmil
Structure of Aquifex aeolicus Argonuate
Descriptor: Argonaute
Authors:Rashid, U.J, Paterok, D, Koglin, A, Gohlke, H, Piehler, J, Chen, J.C.-H.
Deposit date:2006-11-09
Release date:2007-02-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Aquifex aeolicus argonaute highlights conformational flexibility of the PAZ domain as a potential regulator of RNA-induced silencing complex function.
J.Biol.Chem., 282, 2007
3HRK
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BU of 3hrk by Molmil
Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidyl-adenylate complex)
Descriptor: CHLORIDE ION, HISTIDYL-ADENOSINE MONOPHOSPHATE, Histidyl-tRNA synthetase
Authors:Arakaki, T.L, Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-09
Release date:2009-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
J.Mol.Biol., 397, 2010
8A7I
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BU of 8a7i by Molmil
Crystal structure of BRD9 bromodomain in complex with compound EA-89
Descriptor: Bromodomain-containing protein 9, ~{N}-[1,1-bis(oxidanylidene)thian-4-yl]-7-[3-methyl-1-(piperidin-4-ylmethyl)indol-5-yl]-4-oxidanylidene-5-propyl-thieno[3,2-c]pyridine-2-carboxamide
Authors:Faller, M, Zink, F.
Deposit date:2022-06-21
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma.
Blood Cancer J, 12, 2022
3HR3
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BU of 3hr3 by Molmil
Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA
Descriptor: 5'-D(*GP*CP*GP*(US4)P*(OMU))P*AP*CP*GP*C)-3'
Authors:Egli, M, Pallan, P.S.
Deposit date:2009-06-08
Release date:2009-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.
J.Am.Chem.Soc., 131, 2009
3HRI
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BU of 3hri by Molmil
Histidyl-tRNA synthetase (apo) from Trypanosoma brucei
Descriptor: Histidyl-tRNA synthetase
Authors:Arakaki, T.L, Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2009-06-09
Release date:2009-12-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.
J.Mol.Biol., 397, 2010
7VFT
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BU of 7vft by Molmil
Crystal structure of rGGGC(CAG)5GUCC oligo
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*AP*GP*CP*AP*GP*GP*UP*CP*C)-3')
Authors:An, Y, Chan, H.Y.E, Ngo, J.C.K.
Deposit date:2021-09-13
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases.
Nucleic Acids Res., 50, 2022
1RC7
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BU of 1rc7 by Molmil
Crystal structure of RNase III Mutant E110K from Aquifex Aeolicus complexed with ds-RNA at 2.15 Angstrom Resolution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3', Ribonuclease III
Authors:Blaszczyk, J, Gan, J, Ji, X.
Deposit date:2003-11-03
Release date:2004-03-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA.
Structure, 12, 2004
1RC5
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BU of 1rc5 by Molmil
CRYSTAL STRUCTURE OF MG(II)-COMPLEX OF RNASE III ENDONUCLEASE DOMAIN FROM AQUIFEX AEOLICUS AT 2.30 ANGSTROM RESOLUTION
Descriptor: MAGNESIUM ION, Ribonuclease III
Authors:Blaszczyk, J, Gan, J, Ji, X.
Deposit date:2003-11-03
Release date:2004-03-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA.
Structure, 12, 2004
3KLM
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BU of 3klm by Molmil
17beta-HSD1 in complex with DHT
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Estradiol 17-beta-dehydrogenase 1, GLYCEROL
Authors:Mazumdar, M.
Deposit date:2009-11-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.
Mol.Endocrinol., 24, 2010
8BJW
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BU of 8bjw by Molmil
Structure of Tupaia Paramyxovirus C protein
Descriptor: DI(HYDROXYETHYL)ETHER, Protein C
Authors:Bourhis, J.M, Jamin, M.
Deposit date:2022-11-08
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Orthoparamyxovirinae C Proteins Have a Common Origin and a Common Structural Organization.
Biomolecules, 13, 2023
1R4K
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BU of 1r4k by Molmil
Solution Structure of the Drosophila Argonaute 1 PAZ Domain
Descriptor: Argonaute 1
Authors:Yan, K.S, Yan, S, Farooq, A, Han, A, Zeng, L, Zhou, M.-M.
Deposit date:2003-10-07
Release date:2003-12-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and conserved RNA binding of the PAZ domain
Nature, 426, 2003
3LC0
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BU of 3lc0 by Molmil
Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidine complex)
Descriptor: HISTIDINE, Histidyl-tRNA synthetase
Authors:Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2010-01-08
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs.
J.Mol.Biol., 397, 2010
2A0P
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BU of 2a0p by Molmil
Crystal structure of RNA oligomer containing 4'-thioribose
Descriptor: 5'-R(*CP*CP*(S4C)P*CP*GP*GP*GP*G)-3'
Authors:Haeberli, P, Berger, I, Pallan, P.S, Egli, M.
Deposit date:2005-06-16
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Syntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine
Nucleic Acids Res., 33, 2005
2A11
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BU of 2a11 by Molmil
Crystal Structure of Nuclease Domain of Ribonuclase III from Mycobacterium Tuberculosis
Descriptor: CALCIUM ION, Ribonuclease III
Authors:Akey, D.L, Berger, J.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-06-17
Release date:2005-07-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A
Protein Sci., 14, 2005
5E3H
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BU of 5e3h by Molmil
Structural Basis for RNA Recognition and Activation of RIG-I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ...
Authors:Jiang, F, Miller, M.T, Marcotrigiano, J.
Deposit date:2015-10-02
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of RNA recognition and activation by innate immune receptor RIG-I.
Nature, 479, 2011
6ANV
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BU of 6anv by Molmil
Crystal structure of anti-CRISPR protein AcrF1
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Yang, H, Patel, D.J.
Deposit date:2017-08-14
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.265 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6ANW
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BU of 6anw by Molmil
Crystal structure of anti-CRISPR protein AcrF10
Descriptor: anti-CRISPR protein AcrF10
Authors:Yang, H, Patel, D.J.
Deposit date:2017-08-14
Release date:2017-10-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B46
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BU of 6b46 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF1
Descriptor: Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy3, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B44
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BU of 6b44 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound target dsDNA
Descriptor: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
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BU of 6b45 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex
Descriptor: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B47
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BU of 6b47 by Molmil
Cryo-EM structure of Type I-F CRISPR crRNA-guided Csy surveillance complex with bound anti-CRISPR protein AcrF2
Descriptor: Anti-CRISPR protein AcrF2, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ...
Authors:Guo, T.W, Bartesaghi, A, Yang, H, Falconieri, V, Rao, P, Merk, A, Fox, T, Earl, L, Patel, D.J, Subramaniam, S.
Deposit date:2017-09-25
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017

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