3KLM

17beta-HSD1 in complex with DHT

Summary for 3KLM

• Entry DOI: 10.2210/pdb3klm/pdb
• Descriptor: Estradiol 17-beta-dehydrogenase 1, 5-ALPHA-DIHYDROTESTOSTERONE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: dht, lipid synthesis, steroid biosynthesis, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P14061
• Total number of polymer chains: 1
• Total formula weight: 35356.48

Authors

Mazumdar, M. (deposition date: 2009-11-08, release date: 2010-04-21, Last modification date: 2024-02-21)

• Primary citation: Aka, J.A.,Mazumdar, M.,Chen, C.Q.,Poirier, D.,Lin, S.X.; 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production.; Mol.Endocrinol., 24:832-845, 2010; PubMed: 20172961; DOI: 10.1210/me.2009-0468

Experimental method

X-RAY DIFFRACTION (1.7 Å)